Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.47 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.47 |
| ▸ | F3 | P13726 | 2/20 | 0.47 |
| ▸ | TNKS | O95271 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6990829 | 0.78 | MAPT (0.55) | MAPTHDAC3ALDH1A1HDAC4HDAC1 | |
| SCHEMBL6990827 | 0.78 | MAPT (0.55) | MAPTHDAC3ALDH1A1HDAC4HDAC1 | |
| SCHEMBL9294571 | 0.75 | ALDH1A1 (0.42) | MAPTALDH1A1PLIN1LMNARECQL | |
| SCHEMBL11773229 | 0.73 | FBP1 (0.46) | MAPTALDH1A1CYP2C9SMN1; SMN2TSHR | |
| SCHEMBL11773221 | 0.73 | FBP1 (0.46) | MAPTALDH1A1CYP2C9SMN1; SMN2TSHR | |
| SCHEMBL4864694 | 0.72 | ALDH1A1 (0.48) | MAPTALDH1A1RECQLCYP1A2CYP2C9 | |
| SCHEMBL4864709 | 0.72 | ALDH1A1 (0.48) | MAPTALDH1A1RECQLCYP1A2CYP2C9 | |
| SCHEMBL11022953 | 0.70 | AKR1C1 (0.46) | MAPTALDH1A1PLIN1LMNARECQL | |
| SCHEMBL25422533 | 0.68 | MEN1 (0.42) | ALDH1A1LMNARECQLCYP2C9SMN1; SMN2 | |
| SCHEMBL10490115 | 0.68 | MCL1 (0.42) | MAPTALDH1A1PLIN1LMNARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0583417-B1 | CROSSLINKED POLED POLYMERS FOR NONLINEAR OPTIC APPLICATIONS AND METHOD OF MAKING THEM | DU PONT (US) | 1997-01-29 | — | — | EP | disclosed |
| EP-0595921-A1 | PREPARATION OF NONLINEAR OPTICAL ELEMENTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-05-11 | — | — | EP | disclosed |
| EP-0583417-A1 | CROSSLINKED POLED POLYMERS FOR NONLINEAR OPTIC APPLICATIONS AND METHOD OF MAKING THEM. | DU PONT (US) | 1994-02-23 | — | — | EP | disclosed |
| US-5266651-A | Crosslinked poled polymers for nonlinear optic applications and method of making them | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-11-30 | — | — | US | disclosed |
| WO-1993002384-A1 | PREPARATION OF NONLINEAR OPTICAL ELEMENTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-02-04 | — | — | WO | disclosed |
| WO-1992019654-A1 | CROSSLINKED POLED POLYMERS FOR NONLINEAR OPTIC APPLICATIONS AND METHOD OF MAKING THEM | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-11-12 | — | — | WO | disclosed |
| US-4160078-A | ACYL AZIDE MONOMERS, FREE RADICAL CATALYST | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION, LTD. (IL) | 1979-07-03 | — | — | US | disclosed |