Methacrylic Acid

Methacrylic Acid

SCHEMBL8850985

C=C(C)C(=O)O.C=C(C)C(=O)O.CC(C)C(C)(CO)CO

nearest known ligand 0.34

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Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.34
TSHR P16473 1/20 0.33
TET2 Q6N021 1/20 0.33
ALDH1A1 P00352 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
PIK3CD O00329 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL21831885 0.83 TGFBR1 (0.34) TGFBR1TSHRTET2ALDH1A1TDP1
Methacrylic Acid SCHEMBL28135989 0.80 TGFBR1 (0.35) TGFBR1TSHRTET2ALDH1A1TDP1
Methacrylic Acid SCHEMBL8850937 0.80 TGFBR1 (0.39) TGFBR1TSHRTET2ALDH1A1TDP1
2,2,3-Trimethylbutane SCHEMBL27799314 0.79 SLC7A5 (0.38) TGFBR1TSHRTET2ALDH1A1TDP1
Methacrylic Acid SCHEMBL3802187 0.79 TET2 (0.39) TGFBR1TSHRTET2ALDH1A1TDP1
2,2,3-Trimethylbutane SCHEMBL998330 0.79 SLC7A5 (0.38) TGFBR1TSHRTET2ALDH1A1TDP1
Acrylic Acid SCHEMBL1725904 0.78 LMNA (0.43) TSHRALDH1A1
SCHEMBL1356446 0.78
Methacrylic Acid SCHEMBL28514050 0.77 TET2 (0.38) TGFBR1TSHRTET2ALDH1A1TDP1
Methacrylic Acid SCHEMBL10432815 0.77 TET2 (0.38) TGFBR1TSHRTET2ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5663264-A OF A COPOLYMER CONTAINING AN ALKYLENE OXIDE MONOMER, A POLYFUNCTIONAL (METH)ACRYLATE MONOMER AND A VINYL MONOMER HITACHI CHEMICAL COMPANY, LTD. (JP) 1997-09-02 US claimed
US-5583191-A FORMED OF TRANSPARENT RESIN OBTAINED BY POLYMERIZING MONOMER HAVING ALKYLENE OXIDE GROUP, POLYFUNCTIONAL (METH)ACRYLATE HAVING DIVALENT BRANCED HYDROCARBON GROUP, OPTIONAL ADDITIONAL VINYL MONOMER; HEAT RESISTANCE HITACHI CHEMICAL COMPANY, LTD. (JP) 1996-12-10 US claimed
EP-0661307-B1 Transparent resin and plastic lens HITACHI CHEMICAL CO LTD (JP) 1997-10-15 EP disclosed
US-5663264-A OF A COPOLYMER CONTAINING AN ALKYLENE OXIDE MONOMER, A POLYFUNCTIONAL (METH)ACRYLATE MONOMER AND A VINYL MONOMER HITACHI CHEMICAL COMPANY, LTD. (JP) 1997-09-02 US disclosed
US-5583191-A FORMED OF TRANSPARENT RESIN OBTAINED BY POLYMERIZING MONOMER HAVING ALKYLENE OXIDE GROUP, POLYFUNCTIONAL (METH)ACRYLATE HAVING DIVALENT BRANCED HYDROCARBON GROUP, OPTIONAL ADDITIONAL VINYL MONOMER; HEAT RESISTANCE HITACHI CHEMICAL COMPANY, LTD. (JP) 1996-12-10 US disclosed
EP-0661307-A2 Transparent resin and plastic lens HITACHI CHEMICAL CO., LTD. (JP) 1995-07-05 EP disclosed