Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 9/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.32 |
| ▸ | POLB | P06746 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL50811 | 0.83 | TDP1 (0.48) | TDP1CYP3A4ALDH1A1HSD17B10TSHR | |
| Iodide SCHEMBL16916967 | 0.82 | TDP1 (0.46) | TDP1CYP3A4ALDH1A1HSD17B10TSHR | |
| Phosphine SCHEMBL28474623 | 0.82 | TDP1 (0.46) | TDP1CYP3A4ALDH1A1HSD17B10TSHR | |
| Phenanthrene SCHEMBL984028 | 0.82 | CYP2A6 (0.50) | TDP1CYP3A4ALDH1A1HSD17B10TSHR | |
| Pyridine SCHEMBL10336881 | 0.81 | TDP1 (0.40) | TDP1CYP3A4ALDH1A1HSD17B10TSHR | |
| Formaldehyde SCHEMBL27472811 | 0.79 | ALDH1A1 (0.43) | TDP1CYP3A4ALDH1A1HSD17B10TSHR | |
| Anthracene SCHEMBL28071192 | 0.79 | ALDH1A1 (0.43) | TDP1CYP3A4ALDH1A1HSD17B10TSHR | |
| SCHEMBL28466736 | 0.79 | ALDH1A1 (0.43) | TDP1CYP3A4ALDH1A1HSD17B10TSHR | |
| Oxazole SCHEMBL9615519 | 0.77 | MAPT (0.37) | TDP1CYP3A4ALDH1A1HSD17B10TSHR | |
| SCHEMBL29353155 | 0.77 | HPRT1 (0.52) | TDP1CYP3A4ALDH1A1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624786-A | HIGH CONTRAST AND DEFINITION, HYDRAZINE COMPOUND OR A TETRAZOLIUM COMPOUND | KONICA CORPORATION (JP) | 1997-04-29 | — | — | US | disclosed |