Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | F12 | P00748 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | NCF1 | P14598 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Naphthalene SCHEMBL303703 | 0.87 | CYP2A6 (0.40) | CYP2A6ALDH1A1 | |
| Phenazine SCHEMBL18063602 | 0.83 | MAPT (0.50) | ALDH1A1HSD17B10TDP1MAPTNQO2 | |
| Anthracene SCHEMBL27585398 | 0.83 | ALDH1A1 (0.37) | CYP2A6ALDH1A1HSD17B10TDP1CYP3A4 | |
| Hydrochlorthiazide SCHEMBL8852029 | 0.82 | TDP1 (0.35) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 | |
| Pyrene SCHEMBL17144401 | 0.81 | HSD17B10 (0.48) | ALDH1A1HSD17B10TSHRTDP1CYP3A4 | |
| Hydrochlorthiazide SCHEMBL2541220 | 0.81 | PLAU (0.41) | CYP2A6ALDH1A1HSD17B10TSHRCYP3A4 | |
| Naphthalene SCHEMBL3934202 | 0.79 | TSHR (0.38) | CYP2A6TSHRTDP1CYP3A4 | |
| Dibenzothiophene SCHEMBL27966834 | 0.78 | GPR3 (0.56) | ALDH1A1HSD17B10TDP1HIF1AMAPT | |
| Dibenzothiophene SCHEMBL27966651 | 0.78 | GPR3 (0.56) | ALDH1A1HSD17B10TDP1HIF1AMAPT | |
| Hydrochlorthiazide SCHEMBL26114764 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2984079-B1 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES | POWER OLEDS LTD (GB) | 2020-07-01 | — | — | EP | disclosed |
| US-10439147-B2 | Heterocyclic compounds and their use in electro-optical or opto-electronic devices | POWER OLEDS LIMITED (GB) | 2019-10-08 | — | — | US | disclosed |
| CN-105189475-B | Heterocyclic compounds and their use in electro-optical or opto-electronic devices | 动力欧勒德斯有限公司 | 2018-12-21 | — | — | CN | disclosed |
| US-20180323378-A9 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES | POWER OLEDS LIMITED (GB) | 2018-11-08 | — | — | US | disclosed |
| CN-108017645-A | A kind of perimidine derivative and its application | 北京鼎材科技有限公司 | 2018-05-11 | — | — | CN | disclosed |
| EP-2232611-B1 | BARRIER COATED SUBSTRATE AND ELECTRO-OPTICAL DEVICE | MERCK PATENT GMBH (DE) | 2017-11-01 | — | — | EP | disclosed |
| US-9437828-B2 | Electroluminescent device using azomethine-lithium-complex as electron injection layer | MERCK PATENT GMBH (DE) | 2016-09-06 | — | — | US | disclosed |
| EP-2984079-A2 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES | Power Oleds Limited (GB) | 2016-02-17 | — | — | EP | disclosed |
| US-20160035983-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES | POWER OLEDS LTD (GB) | 2016-02-04 | — | — | US | disclosed |
| US-9252383-B2 | Cathode coating | MERCK PATENT GMBH (DE) | 2016-02-02 | — | — | US | disclosed |
| US-4796971-A | CHARGE TRANSFER COMPOUND ON CROSSLINKED MATRIX | EASTMAN KODAK COMPANY (US) | 1989-01-10 | — | — | US | disclosed |
| US-4792208-A | POLAR ALIGNED NONCENTROSYMMETRIC MOLECULAR DIPOLES; SULFONYL MOIETY AS ELECTRON ACCEPTOR | EASTMAN KODAK COMPANY (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0281381-A2 | Electroluminescent device with modified thin film luminescent zone | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1988-09-07 | — | — | EP | disclosed |
| US-4769292-A | Electroluminescent device with modified thin film luminescent zone | EASTMAN KODAK COMPANY (US) | 1988-09-06 | — | — | US | disclosed |
| EP-0276566-A1 | Radiographic element exhibiting reduced crossover | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1988-08-03 | — | — | EP | disclosed |
| EP-0269398-A2 | Enhanced imaging composition containing an azinium activator | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1988-06-01 | — | — | EP | disclosed |
| EP-0269397-A2 | Dye sensitized photographic imaging system | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1988-06-01 | — | — | EP | disclosed |
| US-4743531-A | PHOTORESISTS | EASTMAN KODAK COMPANY (US) | 1988-05-10 | — | — | US | disclosed |
| US-4743528-A | Enhanced imaging composition containing an azinium activator | EASTMAN KODAK COMPANY (US) | 1988-05-10 | — | — | US | disclosed |
| US-4743530-A | FILM FORMER, QUATERNIZED AZINIUM SALT ACTIVATOR, PHOTOSENSITIZER DYE | EASTMAN KODAK COMPANY (US) | 1988-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180323378-A9 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES | NAT1, SLCO2A1, SLCO2B1 | CYP2A6 1385/4885ALDH1A1 789/4885HSD17B10 1935/4885 |
| US-10439147-B2 | Heterocyclic compounds and their use in electro-optical or opto-electronic devices | NAT1, SLCO2A1, SLCO2B1 | CYP2A6 1385/4885ALDH1A1 789/4885HSD17B10 1935/4885 |
| US-20160035983-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES | NAT1, SLCO2A1, SLCO2B1 | CYP2A6 1385/4885ALDH1A1 789/4885HSD17B10 1935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.