Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8851859 | 0.88 | — | — | |
| SCHEMBL6967400 | 0.85 | — | — | |
| SCHEMBL24654499 | 0.83 | CHRM2 (0.37) | CHRM2HRH3 | |
| SCHEMBL8851109 | 0.82 | ALDH1A1 (0.35) | — | |
| SCHEMBL4687426 | 0.82 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL3323907 | 0.79 | HRH4 (0.40) | CHRM2HRH3 | |
| SCHEMBL6961851 | 0.79 | CHRM2 (0.48) | CHRM2 | |
| SCHEMBL13744684 | 0.78 | CHRM2 (0.33) | CHRM2 | |
| SCHEMBL8852107 | 0.77 | PRMT3 (0.32) | — | |
| SCHEMBL8851306 | 0.77 | KDM4E (0.41) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618814-A | Trisubstituted pyrimido [5,4-d] pyrimidines for modulating multi-drug resistance and pharmaceutical compositions containing these compounds | DR. KARL THOMAE GMBH (DE) | 1997-04-08 | — | — | US | disclosed |
| EP-0645390-A1 | Trisubstituted pyrimido 5,4-d pyrimidines for modulating multidrug resistance, drugs containing these compounds and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1995-03-29 | — | — | EP | disclosed |