Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2454271 | 0.83 | CYP2A6 (0.44) | CYP2A6DPP4LMNATSHRNPC1 | |
| SCHEMBL1752721 | 0.83 | MEN1 (0.39) | CYP2A6LMNATSHRNPC1RAB9A | |
| SCHEMBL29883244 | 0.83 | CYP2A6 (0.67) | CYP2A6DPP4LMNATSHRNPC1 | |
| SCHEMBL671133 | 0.83 | CYP2A6 (0.67) | CYP2A6DPP4LMNATSHRNPC1 | |
| SCHEMBL29802156 | 0.83 | CYP2A6 (0.67) | CYP2A6DPP4LMNATSHRNPC1 | |
| Hydrogen Sulfide SCHEMBL8574751 | 0.80 | CYP2A6 (0.63) | CYP2A6DPP4LMNATSHRNPC1 | |
| Ammonia Solution, Strong SCHEMBL735046 | 0.80 | CYP2A6 (0.63) | CYP2A6DPP4LMNATSHRNPC1 | |
| Hydrogen Sulfide SCHEMBL9195473 | 0.80 | CYP2A6 (0.63) | CYP2A6DPP4LMNATSHRNPC1 | |
| SCHEMBL10794320 | 0.78 | CYP2A6 (0.55) | CYP2A6DPP4LMNATSHRNPC1 | |
| SCHEMBL970761 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5648549-A | Process for the preparation of secondary arylphosphines | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-07-15 | — | — | US | claimed |
| US-5648549-A | Process for the preparation of secondary arylphosphines | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-07-15 | — | — | US | disclosed |