Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | DPP4 | P27487 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | PTPRC | P08575 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29802156 | 0.96 | CYP2A6 (0.67) | CYP2A6LMNATSHRDPP4NPC1 | |
| SCHEMBL29883244 | 0.96 | CYP2A6 (0.67) | CYP2A6LMNATSHRDPP4NPC1 | |
| SCHEMBL671133 | 0.96 | CYP2A6 (0.67) | CYP2A6LMNATSHRDPP4NPC1 | |
| Hydrogen Sulfide SCHEMBL8574751 | 0.93 | CYP2A6 (0.63) | CYP2A6LMNATSHRDPP4NPC1 | |
| Hydrogen Sulfide SCHEMBL9195473 | 0.93 | CYP2A6 (0.63) | CYP2A6LMNATSHRDPP4NPC1 | |
| Ethyne SCHEMBL9861738 | 0.90 | CYP2A6 (0.60) | CYP2A6LMNATSHRDPP4NPC1 | |
| SCHEMBL10794320 | 0.84 | CYP2A6 (0.55) | CYP2A6LMNATSHRDPP4NPC1 | |
| SCHEMBL381601 | 0.82 | CYP2A6 (0.52) | CYP2A6LMNATSHRDPP4NPC1 | |
| Bicarbonate SCHEMBL4865957 | 0.82 | CYP2A6 (0.59) | CYP2A6LMNATSHRDPP4NPC1 | |
| Bicarbonate SCHEMBL11009844 | 0.82 | CYP2A6 (0.59) | CYP2A6LMNATSHRDPP4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 180 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8709543-B2 | Hydroxyl-terminated thiocarbonate containing compounds, polymers, and copolymers, and polyurethanes and urethane acrylics made therefrom | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2014-04-29 | — | — | US | claimed |
| EP-2585493-A2 | POLYURETHANE BASED PHOTOINITIATORS | Coloplast A/S (DK) | 2013-05-01 | — | — | EP | claimed |
| EP-2585497-A2 | HYDROPHILIC GELS FROM POLYURETHANE-BASED PHOTOINITIATORS | Coloplast A/S (DK) | 2013-05-01 | — | — | EP | claimed |
| US-20130096224-A1 | POLYURETHANE BASED PHOTOINITIATORS | COLOPLAST A/S (DK) | 2013-04-18 | — | — | US | claimed |
| US-20130089582-A1 | HYDROPHILIC GELS FROM POLYURETHANE-BASED PHOTOINITIATORS | COLOPLAST A/S (DK) | 2013-04-11 | — | — | US | claimed |
| US-20120171914-A1 | Hydroxyl-Terminated Thiocarbonate Containing Compounds, Polymers, and Copolymers, and Polyurethanes and Urethane Acrylics Made Therefrom | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2012-07-05 | — | — | US | claimed |
| US-8137754-B2 | Hydroxyl-terminated thiocarbonate containing compounds, polymers, and copolymers, and polyurethanes and urethane acrylics made therefrom | LUBRIZOL ADVANCED MATERIALS, INC. (US) | 2012-03-20 | — | — | US | claimed |
| WO-2011160637-A2 | POLYURETHANE BASED PHOTOINITIATORS | COLOPLAST A/S (DK) | 2011-12-29 | — | — | WO | claimed |
| WO-2011160641-A2 | HYDROPHILIC GELS FROM POLYURETHANE-BASED PHOTOINITIATORS | COLOPLAST A/S (DK) | 2011-12-29 | — | — | WO | claimed |
| US-20080050995-A1 | Hydroxyl-Terminated Thiocarbonate Containing Compounds, Polymers, and Copolymers, and Polyurethanes and Urethane Acrylics Made Therefrom | LUBRIZOL ADVANCED MATERIALS, INC. | 2008-02-28 | — | — | US | claimed |
| EP-1786848-A1 | POLYURETHANES AND URETHANE ACRYLICS MADE FROM HYDROXYL-TERMINATED THIOCARBONATE CONTAINING COMPOUNDS | Noveon, Inc. (US) | 2007-05-23 | — | — | EP | claimed |
| WO-2006020281-A1 | POLYURETHANES AND URETHANE ACRYLICS MADE FROM HYDROXYL-TERMINATED THIOCARBONATE CONTAINING COMPOUNDS | NOVEON, INC. (US) | 2006-02-23 | — | — | WO | claimed |
| EP-1217439-A1 | A protective polycarbonate-polyurethane overcoat for image recording elements | EASTMAN KODAK COMPANY (US) | 2002-06-26 | — | — | EP | claimed |
| US-12163277-B2 | Composite structure with polyurethane layers, which is substantially free of volatile organic compounds | STAHL INTERNATIONAL B.V. (NL) | 2024-12-10 | — | — | US | disclosed |
| US-20240240392-A1 | COMPOSITE STRUCTURE WITH POLYURETHANE LAYERS, WHICH IS SUBSTANTIALLY FREE OF VOLATILE ORGANIC COMPOUNDS | STAHL INTERNATIONAL B.V. (NL) | 2024-07-18 | — | — | US | disclosed |
| EP-3887595-A1 | COMPOSITE STRUCTURE WITH POLYURETHANE LAYERS, WHICH IS SUBSTANTIALLY FREE OF VOLATILE ORGANIC COMPOUNDS | Stahl International B.V. (NL) | 2021-10-06 | — | — | EP | disclosed |
| EP-0208226-A2 | Aqueous-based urethane coating compositions | PERMUTHANE, INC. (US) | 1987-01-14 | — | — | EP | disclosed |
| US-4335029-A | CURED, CHAIN EXTENDED AND ENCAPPED POLYESTERURETHANE COPOLYMERS | WITCO CHEMICAL CORPORATION (US) | 1982-06-15 | — | — | US | disclosed |
| EP-0000927-B1 | PROCESS FOR STABILISING THERMOPLASTIC POLYESTER URETHANES | Mobay Chemical Corporation (US) | 1981-08-26 | — | — | EP | disclosed |
| EP-0000927-A1 | Process for stabilising thermoplastic polyester urethanes | Mobay Chemical Corporation (US) | 1979-03-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120171914-A1 | Hydroxyl-Terminated Thiocarbonate Containing Compounds, Polymers, and Copolymers, and Polyurethanes and Urethane Acrylics Made Therefrom | ALKBH3, HAAO, BHMT2 | CYP2A6 890/4885LMNA 4005/4885TSHR 3660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.