SCHEMBL8853306

SCHEMBL8853306

CC1c2ccccc2-c2c1cccc2C(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.38
ALDH1A1 P00352 1/20 0.36
TSHR P16473 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
PTPN5 P54829 1/20 0.33
DRD2 P14416 4/20 0.33
DRD4 P21917 4/20 0.33
KIF11 P52732 1/20 0.33
GPR3 P46089 2/20 0.31
HTR7 P34969 1/20 0.31
HTR2B P41595 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5352091 0.77 CA2 (0.34) CA2ALDH1A1TSHRTDP1GABRA1
Hydrochloric Acid SCHEMBL5352797 0.76 HTR2A (0.35) CA2ALDH1A1TSHRTDP1GABRA1
Hydrochloric Acid SCHEMBL5351373 0.76 HTR2A (0.35) CA2ALDH1A1TSHRTDP1GABRA1
SCHEMBL3828188 0.74 CA2 (0.36) CA2ALDH1A1TSHRTDP1KMT2A
SCHEMBL8857101 0.74 BCHE (0.37)
SCHEMBL23443980 0.73 PBRM1 (0.36) CA2ALDH1A1DRD2DRD4GPR3
SCHEMBL26972868 0.73 CA2 (0.36) CA2ALDH1A1TSHRTDP1KMT2A
SCHEMBL29641604 0.72 GPR3 (0.52) DRD2DRD4GPR3HTR7HTR2B
SCHEMBL40599 0.72 GPR3 (0.52) DRD2DRD4GPR3HTR7HTR2B
SCHEMBL8857018 0.72 HTR2A (0.35) CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5670589-A COORDINATION POLYMERIZATION CATALYST PHILLIPS PETROLEUM COMPANY (US) 1997-09-23 US disclosed