Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | VHL | P40337 | 1/20 | 0.47 |
| ▸ | ELOC | Q15369 | 1/20 | 0.47 |
| ▸ | ELOB | Q15370 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 2/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8853550 | 0.90 | HDAC1 (0.57) | KMT2AMAPTMEN1GAAHDAC1 | |
| SCHEMBL9629595 | 0.81 | HDAC1 (0.48) | KMT2AMAPTMEN1HDAC1HDAC8 | |
| SCHEMBL9629602 | 0.81 | KMT2A (0.53) | KMT2AMEN1GAAHDAC1HDAC8 | |
| SCHEMBL7454625 | 0.80 | HTT (0.59) | KMT2AMAPTMEN1GAAAHR | |
| SCHEMBL9628766 | 0.78 | MAOA (0.55) | KMT2AHDAC1HDAC8HDAC6TP53 | |
| SCHEMBL9629024 | 0.78 | KIF11 (0.47) | MAPTHDAC1HDAC8HDAC6NOX1 | |
| SCHEMBL9628996 | 0.77 | MAPT (0.53) | KMT2AMAPTMEN1GAAHDAC1 | |
| SCHEMBL9628745 | 0.76 | KMT2A (0.46) | KMT2AMAPTMEN1HDAC1HDAC8 | |
| SCHEMBL9405611 | 0.73 | AHR (0.66) | KMT2AMAPTMEN1GAAAHR | |
| SCHEMBL5507140 | 0.71 | HDAC1 (0.57) | KMT2AMAPTHDAC1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0340581-B1 | PROCESS FOR THE CHLORINATION IN THE NUCLEUS OF AROMATIC HYDROCARBONS | BAYER AG (DE) | 1992-03-18 | — | — | EP | disclosed |
| US-4925994-A | Process for the ring chlorination of aromatic hydrocarbons | BAYER AKTIENGESELLSCHAFT (DE) | 1990-05-15 | — | — | US | disclosed |
| EP-0340581-A2 | Process for the chlorination in the nucleus of aromatic hydrocarbons | BAYER AG (DE) | 1989-11-08 | — | — | EP | disclosed |