Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 4/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.36 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.33 |
| ▸ | CBFB | Q13951 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4979332 | 0.89 | ESR1 (0.40) | MAOAMAOBSMN1; SMN2ESR1ESR2 | |
| SCHEMBL9668468 | 0.84 | ESR2 (0.47) | MAOAMAOBSMN1; SMN2ESR1ESR2 | |
| SCHEMBL9863151 | 0.84 | ESR1 (0.47) | MAOAMAOBESR1ESR2 | |
| SCHEMBL10339321 | 0.80 | SMN1; SMN2 (0.41) | SMN1; SMN2ADRA2AMMP13 | |
| SCHEMBL8855985 | 0.79 | KCNH2 (0.38) | SMN1; SMN2 | |
| SCHEMBL218213 | 0.76 | SMN1; SMN2 (0.50) | SMN1; SMN2ADRA2A | |
| SCHEMBL186365 | 0.75 | KCNH2 (0.43) | SMN1; SMN2ESR1ESR2MAPTRAB9A | |
| SCHEMBL23041422 | 0.74 | SMN1; SMN2 (0.41) | SMN1; SMN2MMP13 | |
| SCHEMBL381604 | 0.74 | SMN1; SMN2 (0.49) | SMN1; SMN2ADRA2A | |
| Hydrochloric Acid SCHEMBL9668585 | 0.73 | KCNH2 (0.42) | SMN1; SMN2ESR1ESR2MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5616659-A | Low flammability thermoset polymers | SOUTHWEST RESEARCH INSTITUTE (US) | 1997-04-01 | — | — | US | disclosed |