SCHEMBL381604

SCHEMBL381604

c1ccc(-c2ccccc2C2=NCCO2)c(C2=NCCO2)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.49
KCNN4 O15554 1/20 0.42
ADRA2A P08913 3/20 0.38
ADRA2B P18089 3/20 0.38
ADRA2C P18825 3/20 0.38
MMP12 P39900 1/20 0.37
TUBB4A P04350 2/20 0.33
TUBB P07437 2/20 0.33
TUBA3C P0DPH7 2/20 0.33
TUBA1B P68363 2/20 0.33
TUBA4A P68366 2/20 0.33
TUBB4B P68371 2/20 0.33
TUBB3 Q13509 2/20 0.33
TUBB2A Q13885 2/20 0.33
TUBB8 Q3ZCM7 2/20 0.33
TUBA3E Q6PEY2 2/20 0.33
TUBA1A Q71U36 2/20 0.33
TUBA1C Q9BQE3 2/20 0.33
TUBB6 Q9BUF5 2/20 0.33
TUBB2B Q9BVA1 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29420719 0.98 SMN1; SMN2 (0.50) SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C
SCHEMBL218213 0.98 SMN1; SMN2 (0.50) SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C
SCHEMBL961794 0.88 ADRA2A (0.48) SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C
SCHEMBL2570914 0.87 NOS3 (0.40) SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C
SCHEMBL27820210 0.86 SMN1; SMN2 (0.43) SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C
SCHEMBL2572924 0.84 NOS3 (0.41) SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C
SCHEMBL8855966 0.84 SMN1; SMN2 (0.55) SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C
SCHEMBL25218345 0.84 SMN1; SMN2 (0.44) SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C
SCHEMBL7452092 0.84 ALDH1A1 (0.44) SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C
SCHEMBL7831181 0.84 NISCH (0.44) SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 279 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017116271-A1 A COMPOSITION OF A CONCENTRATE AND A METHOD OF INCREASING POLYMER VISCOSITY PUBLIC JOINT STOCK COMPANY "SIBUR HOLDING" (RU) 2017-07-06 WO claimed
US-20070184264-A1 Flame-retardant polyester artificial hair KANEKA CORPORATION (JP) 2007-08-09 US claimed
US-20240199930-A1 ONE-PACK TYPE ADHESIVE AGENT COMPOSITION AND CURED PRODUCT AGC Inc. (JP) 2024-06-20 US disclosed
US-20240199929-A1 TWO-PACK TYPE ADHESIVE COMPOSITION AND CURED OBJECT AGC Inc. (JP) 2024-06-20 US disclosed
EP-4379014-A1 ONE-PACK TYPE ADHESIVE AGENT COMPOSITION AND CURED PRODUCT AGC INC. (JP) 2024-06-05 EP disclosed
EP-4379015-A1 TWO-PACK TYPE ADHESIVE COMPOSITION AND CURED OBJECT AGC INC. (JP) 2024-06-05 EP disclosed
WO-2024043326-A1 HYDROPHILIC OIL REPELLENT POLYMER 住友化学株式会社 2024-02-29 WO disclosed
EP-3967724-B1 POLYCARBONATE RESIN COMPOSITION MITSUBISHI ENG PLASTICS CORP (JP) 2024-02-28 EP disclosed
US-11892104-B2 Flexible tube for endoscopes and method for producing same FUJIFILM CORPORATION (JP) 2024-02-06 US disclosed
WO-2023233962-A1 ADHESIVE COMPOSITION AND ARTICLE AGC株式会社 2023-12-07 WO disclosed
WO-2023223701-A1 COMPOSITION 住友化学株式会社 2023-11-23 WO disclosed
US-20050014870-A1 Resin composition SONY CORPORATION (JP) 2005-01-20 US disclosed
EP-1498460-A1 BIODEGRADABLE FLAME RETARDANT COMPOSITE COMPOSITION AND PROCESS FOR PRODUCING THE SAME Sony Corporation (JP) 2005-01-19 EP disclosed
US-20040254270-A1 Flame-retardant resin composition POLYPLASTICS CO., LTD. (JP) 2004-12-16 US disclosed
US-20040242803-A1 Resin composition and molded article, film, and fiber each comprising the same TORAY INDUSTRIES, INC. (JP) 2004-12-02 US disclosed
EP-1466946-A1 FLAME-RETARDANT RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 2004-10-13 EP disclosed
EP-1445282-A1 RESIN COMPOSITION AND MOLDED ARTICLE FILM AND FIBER EACH COMPRISING THE SAME TORAY INDUSTRIES, INC. (JP) 2004-08-11 EP disclosed
US-6740402-B2 HAVING RESISTANCES TO HYDROLYSIS AND FATIGUE FROM FLEXING AT HIGH LEVELS AND USABLE FOR APPLICATIONS OF PAPERMAKING CANVAS, TIRE CORD AND STERILIZED FABRICS TEIJIN LIMITED (JP) 2004-05-25 US disclosed
US-20030143397-A1 Having resistances to hydrolysis and fatigue from flexing at high levels and usable for applications of papermaking canvas, tire cord and sterilized fabrics TEIJIN LIMITED (JP) 2003-07-31 US disclosed
EP-1304402-A1 POLYESTER FIBER TEIJIN LIMITED (JP) 2003-04-23 EP disclosed