SCHEMBL218213

SCHEMBL218213

c1ccc(C2=NCCO2)c(C2=NCCO2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.50
KCNN4 O15554 1/20 0.44
ADRA2A P08913 2/20 0.39
ADRA2B P18089 2/20 0.39
ADRA2C P18825 2/20 0.39
MMP12 P39900 1/20 0.38
ITGB2 P05107 1/20 0.35
ICAM1 P05362 1/20 0.35
ITGAL P20701 1/20 0.35
TUBB4A P04350 3/20 0.34
TUBB P07437 3/20 0.34
TUBA3C P0DPH7 3/20 0.34
TUBA1B P68363 3/20 0.34
TUBA4A P68366 3/20 0.34
TUBB4B P68371 3/20 0.34
TUBB3 Q13509 3/20 0.34
TUBB2A Q13885 3/20 0.34
TUBB8 Q3ZCM7 3/20 0.34
TUBA3E Q6PEY2 3/20 0.34
TUBA1A Q71U36 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29420719 1.00 SMN1; SMN2 (0.50) SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C
SCHEMBL381604 0.98 SMN1; SMN2 (0.49) SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C
SCHEMBL961794 0.90 ADRA2A (0.48) SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C
SCHEMBL8855966 0.86 SMN1; SMN2 (0.55) SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C
SCHEMBL2572924 0.86 NOS3 (0.41) SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C
SCHEMBL25218345 0.86 SMN1; SMN2 (0.44) SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C
SCHEMBL7452092 0.86 ALDH1A1 (0.44) SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C
SCHEMBL8638335 0.86 SMN1; SMN2 (0.44) SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C
SCHEMBL7831181 0.86 NISCH (0.44) SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C
SCHEMBL31048511 0.86 NISCH (0.44) SMN1; SMN2KCNN4ADRA2AADRA2BADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1064 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12252572-B2 Method for improving adhesion in and between layers of additive manufactured articles LUMAS POLYMERS LLC (US) 2025-03-18 US claimed
CN-119061517-A Modified polyester fiber material, preparation method thereof and application thereof in backpack 广东恩典皮具服饰科技股份有限公司 2024-12-03 CN claimed
CN-117659565-A Lightweight alcoholysis-resistant automobile water chamber and preparation method thereof 宜宾凯翼汽车有限公司 2024-03-08 CN claimed
EP-4320184-A1 FLAME RETARDANT POLYAMIDE COMPOSITIONS, USES OF SAME AND PROCESSES FOR THE PREPARATION THEREOF ARKEMA FRANCE (FR) 2024-02-14 EP claimed
CN-117230642-A Antibacterial non-woven fabric bag and processing technology thereof 温州碧亮制袋有限公司 2023-12-15 CN claimed
WO-2023236901-A1 METHOD FOR SYNTHESIZING BIODEGRADABLE BLOCK COPOLYESTER AND BLOCK COPOLYESTER 惠州博科环保新材料有限公司 2023-12-14 WO claimed
WO-2023236862-A1 METHOD FOR SYNTHESIZING BIODEGRADABLE BLOCK COPOLYESTER AND BLOCK COPOLYESTER 惠州博科环保新材料有限公司 2023-12-14 WO claimed
CN-117164854-A Cross-linked polyimide and preparation method thereof 中国科学院长春应用化学研究所 2023-12-05 CN claimed
EP-3131946-B1 METHOD FOR MANUFACTURING A THERMOPLASTIC MATERIAL MADE FROM SEMI-CRYSTALLINE POLYAMIDE ARKEMA FRANCE (FR) 2023-11-22 EP claimed
CN-113956454-B Phosphorus-nitrogen-fluorine flame-retardant oligomer, preparation method thereof, flame-retardant PBT (polybutylene terephthalate) polyester and preparation method thereof 中国石油化工股份有限公司 2023-06-09 CN claimed
US-5631070-A MOLDED PRODUCT CONTAINING AROMATIC POLYAMIDE, POLYPHENYLENE ETHER MODIFIED WITH UNSATURATED ALIPHATIC CARBOXYLIC ACID OR ANHYDRIDE, LIQUID CRYSTALLINE COPOLYESTER, PHENYLENEBISOXAZOLINE, INORGANIC FILLER FUJITSU LIMITED (JP) 1997-05-20 US claimed
EP-0438128-B1 Polymer blend composition for melt molding UNITIKA LTD (JP) 1996-05-29 EP claimed
US-5470909-A Polyphenylene ether modified with unsaturated acid and liquid crystal polyester FUJITSU LIMITED (JP) 1995-11-28 US claimed
US-5324795-A Thickener added to a liquid crystal and non liquid crystal UNITIKA LTD. (JP) 1994-06-28 US claimed
US-5173357-A Tear-resistant polyester film and laminated sheets comprised of the same POLYPLASTICS CO., LTD. (JP) 1992-12-22 US claimed
US-5091259-A Flame retardant, flexible POLYPLASTICS CO., LTD. (JP) 1992-02-25 US claimed
EP-0438128-A2 Polymer blend composition for melt molding UNITIKA LTD. (JP) 1991-07-24 EP claimed
US-4987167-A Flexible dielectric coverings POLYPLASTICS CO., LTD. (JP) 1991-01-22 US claimed
US-4652620-A THERMOSETTING RESINS ASHLAND OIL, INC. (US) 1987-03-24 US claimed
US-4430491-A THERMOSETTING, MELTS, PHENOLIC OLIGOMER, COMPOUND WITH AT LEAST TW ASHLAND OIL, INC. (US) 1984-02-07 US claimed