Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | IL6 | P05231 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8854405 | 0.90 | NFE2L2 (0.36) | ATMMAOBNFE2L2LMNASMN1; SMN2 | |
| SCHEMBL8854716 | 0.88 | KCNK3 (0.39) | ATMLMNAKMT2AKDM4EMRGPRX4 | |
| SCHEMBL8854428 | 0.85 | SCN8A (0.33) | ATMKMT2AKDM4EMEN1TSHR | |
| SCHEMBL8735584 | 0.85 | ATM (0.36) | ATMMAOBNFE2L2LMNASMN1; SMN2 | |
| SCHEMBL8854651 | 0.84 | GABRA1 (0.36) | ATMMAOBLMNASMN1; SMN2KMT2A | |
| SCHEMBL8854450 | 0.84 | PTGES2 (0.33) | — | |
| SCHEMBL8854453 | 0.82 | ALDH1A1 (0.32) | — | |
| SCHEMBL27362599 | 0.81 | MAOB (0.34) | MAOB | |
| SCHEMBL8854456 | 0.80 | AR (0.32) | — | |
| SCHEMBL8854565 | 0.80 | ATM (0.36) | ATMMAOBNFE2L2LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1173282-A | Herbicidal method utilizing phosphosulfonate herbicides and oxime ether safeners | ROHM & HAAS (US) | 1998-02-18 | — | — | CN | claimed |
| US-5693590-A | PLANT GROWTH REGULATOR | ROHM AND HAAS COMPANY (US) | 1997-12-02 | — | — | US | claimed |
| CN-1133120-A | Combination containing phosphine sulfonate ester herbicide and dichloro acetamide safety agent | ROHM & HAAS (US) | 1996-10-16 | — | — | CN | claimed |