SCHEMBL8854429

SCHEMBL8854429

CO[PH](=O)OOS(=O)(=O)c1c(F)cccc1OC(F)(F)F

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 1/20 0.32
KCNK3 O14649 1/20 0.30
KCNK9 Q9NPC2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8854595 0.87 KCNN4 (0.33) KCNN4
SCHEMBL8854439 0.87 KCNN4 (0.33) KCNN4KCNK3KCNK9
SCHEMBL8854621 0.85 HCRTR1 (0.32)
SCHEMBL8854443 0.82 SLC22A12 (0.33)
SCHEMBL8854502 0.81 KCNN4 (0.36) KCNN4KCNK3KCNK9
SCHEMBL8854741 0.80 SLC22A12 (0.38) KCNK3KCNK9
SCHEMBL8854688 0.79
SCHEMBL8854464 0.77 KEAP1 (0.32)
SCHEMBL8854604 0.76 PKM (0.31)
SCHEMBL8854518 0.75 KCNN4 (0.32) KCNN4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5693590-A PLANT GROWTH REGULATOR ROHM AND HAAS COMPANY (US) 1997-12-02 US claimed