SCHEMBL8854464

SCHEMBL8854464

CCc1cccc(F)c1S(=O)(=O)OO[PH](=O)OC

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.32
PKM P14618 2/20 0.32
PKLR P30613 2/20 0.32
KAT6A Q92794 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8854475 0.86 KEAP1 (0.33) KEAP1PKMPKLRKAT6ALMNA
SCHEMBL8854622 0.86 KEAP1 (0.33) KEAP1PKMPKLRKAT6ALMNA
SCHEMBL8854641 0.83 GABRA1 (0.33)
SCHEMBL8854661 0.82
SCHEMBL8854558 0.82 KAT6A (0.31) KAT6A
SCHEMBL8854540 0.81
SCHEMBL8854621 0.81 HCRTR1 (0.32)
SCHEMBL8854519 0.80
SCHEMBL8854462 0.80 FFAR4 (0.34)
SCHEMBL8854604 0.80 PKM (0.31) PKMPKLR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5693590-A PLANT GROWTH REGULATOR ROHM AND HAAS COMPANY (US) 1997-12-02 US claimed