Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 11/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylglyoxal SCHEMBL6452706 | 0.88 | CTSD (0.38) | PTPN1ALDH1A1KDM4EMAPTTDP1 | |
| Methylglyoxal SCHEMBL8854695 | 0.71 | PTPN1 (0.41) | PTPN1ALDH1A1ALOX15KDM4EPOLB | |
| Phthalic Acid SCHEMBL28441584 | 0.69 | ALDH1A1 (0.61) | ALDH1A1ALOX15KDM4EMAPTTDP1 | |
| SCHEMBL11796141 | 0.68 | ALDH1A1 (0.48) | PTPN1ALDH1A1ALOX15KDM4EMAPT | |
| SCHEMBL14893324 | 0.67 | ALDH1A1 (0.56) | PTPN1ALDH1A1ALOX15KDM4EPOLB | |
| SCHEMBL972143 | 0.67 | ALDH1A1 (0.56) | PTPN1ALDH1A1ALOX15KDM4EPOLB | |
| Phthalic Acid SCHEMBL30288540 | 0.65 | ALDH1A1 (0.61) | ALDH1A1ALOX15KDM4EPOLBMAPT | |
| Phthalic Acid SCHEMBL11274547 | 0.65 | ALDH1A1 (0.61) | ALDH1A1ALOX15KDM4EPOLBMAPT | |
| Phthalic Acid SCHEMBL6551340 | 0.65 | ALDH1A1 (0.61) | ALDH1A1ALOX15KDM4EPOLBMAPT | |
| SCHEMBL5524626 | 0.65 | ALDH1A1 (0.48) | PTPN1ALDH1A1ALOX15KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5661139-A | FOR INHIBITING GLYCOSYLATION OF PROTEINS TO PREVENT DISCOLORATION OF THE TEETH | ALTEON INC. (US) | 1997-08-26 | — | — | US | disclosed |
| WO-1996040622-A1 | BIS-(2-ARYL)HYDRAZONES AS INHIBITORS OF THE FORMATION OF ADVANCED GLYCOSYLATION ENDPRODUCTS | ALTEON INC. (US) | 1996-12-19 | — | — | WO | disclosed |
| US-5552400-A | Fused-bicyclic lactams as interleukin-1β converting enzyme inhibitors | STERLING WINTHROP INC. (US) | 1996-09-03 | — | — | US | disclosed |