Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylglyoxal SCHEMBL8854583 | 0.88 | PTPN1 (0.40) | CA1CA2CA9ALDH1A1MAPT | |
| Methylglyoxal SCHEMBL2956982 | 0.75 | CTSD (0.40) | CTSDCA1CA2CA9ALDH1A1 | |
| Methylglyoxal SCHEMBL2950078 | 0.70 | CTSD (0.49) | CTSDCA1CA2CA9ALDH1A1 | |
| Methylglyoxal SCHEMBL8854728 | 0.69 | CTSD (0.47) | CTSDCA1CA2CA9ALDH1A1 | |
| SCHEMBL962276 | 0.68 | ALDH1A1 (0.62) | CTSDCA1CA2CA9ALDH1A1 | |
| SCHEMBL961664 | 0.66 | CTSD (0.50) | CTSDCA1CA2CA9ALDH1A1 | |
| SCHEMBL959908 | 0.66 | CTSD (0.50) | CTSDCA1CA2CA9ALDH1A1 | |
| SCHEMBL10921933 | 0.65 | CTSD (0.49) | CTSDCA1CA2CA9ALDH1A1 | |
| Acetic Acid SCHEMBL27741391 | 0.64 | CTSD (0.60) | CTSDCA1CA2CA9ALDH1A1 | |
| SCHEMBL959111 | 0.64 | CTSD (0.47) | CTSDCA1CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5661139-A | FOR INHIBITING GLYCOSYLATION OF PROTEINS TO PREVENT DISCOLORATION OF THE TEETH | ALTEON INC. (US) | 1997-08-26 | — | — | US | claimed |
| WO-1996040622-A1 | BIS-(2-ARYL)HYDRAZONES AS INHIBITORS OF THE FORMATION OF ADVANCED GLYCOSYLATION ENDPRODUCTS | ALTEON INC. (US) | 1996-12-19 | — | — | WO | claimed |
| EP-1175155-A4 | METHOD FOR REDUCING A SUSCEPTIBILITY TO TUMOR FORMATION INDUCED BY 3-DEOXYGLUCOSONE AND PRECURSORS THEREOF | FOX CHASE CANCER CT (US) | 2005-10-19 | — | — | EP | disclosed |
| EP-1175155-A1 | METHOD FOR REDUCING A SUSCEPTIBILITY TO TUMOR FORMATION INDUCED BY 3-DEOXYGLUCOSONE AND PRECURSORS THEREOF | FOX CHASE CANCER CENTER (US) | 2002-01-30 | — | — | EP | disclosed |
| WO-2000062626-A1 | METHOD FOR REDUCING A SUSCEPTIBILITY TO TUMOR FORMATION INDUCED BY 3-DEOXYGLUCOSONE AND PRECURSORS THEREOF | FOX CHASE CANCER CENTER (US) | 2000-10-26 | — | — | WO | disclosed |
| US-5661139-A | FOR INHIBITING GLYCOSYLATION OF PROTEINS TO PREVENT DISCOLORATION OF THE TEETH | ALTEON INC. (US) | 1997-08-26 | — | — | US | disclosed |