Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 2/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.34 |
| ▸ | CDK2 | P24941 | 2/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.34 |
| ▸ | HTR7 | P34969 | 2/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5157470 | 0.89 | CDK1 (0.38) | HSD17B10LMNAHTTCDK1CCNB1 | |
| SCHEMBL9504245 | 0.85 | MAPT (0.32) | LMNAHTTCDK1CCNB1NPC1 | |
| SCHEMBL5848944 | 0.81 | — | — | |
| SCHEMBL16423545 | 0.79 | CDK1 (0.34) | HSD17B10LMNAHTTCDK1CCNB1 | |
| SCHEMBL5158779 | 0.76 | NPSR1 (0.49) | CDK1CDK2TLR8 | |
| SCHEMBL313536 | 0.74 | MAPT (0.37) | HSD17B10HTTTP53GAA | |
| SCHEMBL6727244 | 0.71 | LMNA (0.38) | HSD17B10LMNAHTTCDK1CCNB1 | |
| SCHEMBL4452232 | 0.70 | CDK1 (0.32) | HSD17B10LMNAHTTCDK1CCNB1 | |
| SCHEMBL1012240 | 0.69 | CDK1 (0.31) | HSD17B10LMNAHTTCDK1CCNB1 | |
| SCHEMBL18944170 | 0.68 | PDE4A (0.52) | LMNANPC1GAARAB9ATLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677380-A | COATING ON IRREGULAR SURFACE MATERIAL COMPRISING ADDITION POLYMER, HEAT CURING AGENT, HALATION PREVENTIVE AGENT, HEATING TO FLUIDIZE AND CURE FILM | TOSOH CORPORATION (JP) | 1997-10-14 | — | — | US | disclosed |