Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | P4HB | P07237 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.32 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.30 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8854990 | 0.89 | PTGS2 (0.43) | GCGRMEN1KMT2AP4HBPTGS2 | |
| SCHEMBL8855130 | 0.82 | GCGR (0.43) | GCGRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL8855066 | 0.81 | PTGS2 (0.39) | GCGRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL8855200 | 0.81 | GCGR (0.40) | GCGRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL8855015 | 0.77 | GCGR (0.34) | GCGRMAPK10MAPK14MAPK9CSNK1D | |
| SCHEMBL9086126 | 0.77 | PTGS2 (0.34) | GCGRNPC1RAB9AMEN1KMT2A | |
| SCHEMBL9084846 | 0.76 | METAP2 (0.35) | GCGRPTGS2METAP2 | |
| SCHEMBL8855005 | 0.71 | GCGR (0.33) | GCGRMAPK10MAPK14MAPK9CSNK1D | |
| SCHEMBL8855084 | 0.71 | PTGS2 (0.44) | GCGRPTGS2 | |
| SCHEMBL8855068 | 0.70 | MEN1 (0.41) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599952-A | A 4-FLUOROBIPHENYL DERIVATIVE | FUJIREBIO INC. (JP) | 1997-02-04 | — | — | US | disclosed |
| US-5481009-A | Methods of producing carboxylic acid ester derivatives and intermediates for use in the methods | FUJIREBIO INC. (JP) | 1996-01-02 | — | — | US | disclosed |
| EP-0643054-A2 | Methods of producing carboxylic acid ester derivatives and intermediates for use in the methods | FUJIREBIO Inc. (JP) | 1995-03-15 | — | — | EP | disclosed |