Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.37 |
| ▸ | HMGCR | P04035 | 3/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | P4HB | P07237 | 2/20 | 0.34 |
| ▸ | OGA | O60502 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | UGCG | Q16739 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8855063 | 0.88 | PTGS2 (0.46) | MEN1KMT2APTGS2HMGCRP4HB | |
| SCHEMBL26005534 | 0.76 | PTGS1 (0.37) | SMN1; SMN2PTGS2PTGS1UGCG | |
| SCHEMBL8855104 | 0.75 | HMGCR (0.34) | PTGS2HMGCRPTGS1METAP2GPR84 | |
| SCHEMBL8855130 | 0.71 | GCGR (0.43) | MEN1NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL22607369 | 0.71 | PTGS1 (0.38) | MEN1KMT2ASMN1; SMN2PTGS2PTGS1 | |
| SCHEMBL13054420 | 0.71 | GABRA1 (0.38) | SMN1; SMN2PTGS2PTGS1 | |
| SCHEMBL8854963 | 0.70 | GCGR (0.34) | MEN1NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL13303318 | 0.69 | GABRA1 (0.41) | SMN1; SMN2PTGS2PTGS1 | |
| SCHEMBL12412397 | 0.69 | PTGS1 (0.37) | SMN1; SMN2PTGS2PTGS1 | |
| SCHEMBL8855101 | 0.69 | HMGCR (0.33) | PTGS2HMGCRGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599952-A | A 4-FLUOROBIPHENYL DERIVATIVE | FUJIREBIO INC. (JP) | 1997-02-04 | — | — | US | disclosed |
| US-5481009-A | Methods of producing carboxylic acid ester derivatives and intermediates for use in the methods | FUJIREBIO INC. (JP) | 1996-01-02 | — | — | US | disclosed |
| EP-0643054-A2 | Methods of producing carboxylic acid ester derivatives and intermediates for use in the methods | FUJIREBIO Inc. (JP) | 1995-03-15 | — | — | EP | disclosed |