Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | GCGR | P47871 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9086520 | 0.89 | GCGR (0.30) | GCGR | |
| SCHEMBL9087026 | 0.83 | — | — | |
| SCHEMBL8855015 | 0.81 | GCGR (0.34) | GCGRTSHR | |
| SCHEMBL8855294 | 0.79 | GCGR (0.43) | GCGR | |
| SCHEMBL8855066 | 0.79 | PTGS2 (0.39) | ALDH1A1PTGS2GCGRKDM4ELMNA | |
| SCHEMBL8855025 | 0.79 | PTGS2 (0.49) | ALDH1A1PTGS2GCGRKDM4ELMNA | |
| SCHEMBL8854995 | 0.78 | GCGR (0.39) | GCGR | |
| SCHEMBL8855003 | 0.77 | ALDH1A1 (0.36) | ALDH1A1PTGS2GCGRKDM4ELMNA | |
| SCHEMBL4499404 | 0.77 | ALDH1A1 (0.39) | ALDH1A1PTGS2KDM4ELMNATSHR | |
| SCHEMBL9084870 | 0.77 | HMGCR (0.38) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599952-A | A 4-FLUOROBIPHENYL DERIVATIVE | FUJIREBIO INC. (JP) | 1997-02-04 | — | — | US | disclosed |
| US-5481009-A | Methods of producing carboxylic acid ester derivatives and intermediates for use in the methods | FUJIREBIO INC. (JP) | 1996-01-02 | — | — | US | disclosed |
| EP-0643054-A2 | Methods of producing carboxylic acid ester derivatives and intermediates for use in the methods | FUJIREBIO Inc. (JP) | 1995-03-15 | — | — | EP | disclosed |