Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 14/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8854995 | 0.89 | GCGR (0.39) | GCGR | |
| SCHEMBL8855015 | 0.82 | GCGR (0.34) | GCGR | |
| SCHEMBL8855007 | 0.79 | ALDH1A1 (0.34) | GCGR | |
| SCHEMBL8855084 | 0.79 | PTGS2 (0.44) | GCGR | |
| SCHEMBL8855130 | 0.79 | GCGR (0.43) | GCGR | |
| SCHEMBL8855290 | 0.77 | GCGR (0.42) | GCGRGABRA1GABRG2GABRB3 | |
| SCHEMBL9086520 | 0.75 | GCGR (0.30) | GCGR | |
| SCHEMBL9087026 | 0.75 | — | — | |
| SCHEMBL2648203 | 0.73 | GCGR (0.65) | GCGRGABRA1GABRG2GABRB3 | |
| SCHEMBL8855104 | 0.72 | HMGCR (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599952-A | A 4-FLUOROBIPHENYL DERIVATIVE | FUJIREBIO INC. (JP) | 1997-02-04 | — | — | US | disclosed |
| US-5481009-A | Methods of producing carboxylic acid ester derivatives and intermediates for use in the methods | FUJIREBIO INC. (JP) | 1996-01-02 | — | — | US | disclosed |
| EP-0643054-A2 | Methods of producing carboxylic acid ester derivatives and intermediates for use in the methods | FUJIREBIO Inc. (JP) | 1995-03-15 | — | — | EP | disclosed |