Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 7/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | GYS1 | P13807 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.31 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8855016 | 0.91 | CCNB2 (0.35) | ARMAOBGYS1FFAR4L3MBTL1 | |
| SCHEMBL8854976 | 0.88 | SSTR5 (0.33) | ARFFAR4SSTR5 | |
| SCHEMBL8854971 | 0.87 | MAOB (0.31) | MAOBGYS1 | |
| SCHEMBL8854959 | 0.86 | MAOB (0.34) | MAOBGYS1FFAR4L3MBTL1SMN1; SMN2 | |
| SCHEMBL8855229 | 0.85 | FFAR4 (0.32) | FFAR4NPC1 | |
| SCHEMBL8855047 | 0.85 | PTGS2 (0.33) | FFAR4 | |
| SCHEMBL8855163 | 0.84 | MAOB (0.33) | MAOBGYS1FFAR4L3MBTL1SMN1; SMN2 | |
| SCHEMBL8854944 | 0.84 | GCGR (0.36) | MAOBGYS1FFAR4NPC1RAB9A | |
| SCHEMBL8855239 | 0.83 | FFAR4 (0.33) | FFAR4 | |
| SCHEMBL8854969 | 0.83 | HMGCR (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599952-A | A 4-FLUOROBIPHENYL DERIVATIVE | FUJIREBIO INC. (JP) | 1997-02-04 | — | — | US | disclosed |
| US-5523460-A | ANTICHOLESTEROL AGENTS | FUJIREBIO INC. (JP) | 1996-06-04 | — | — | US | disclosed |
| US-5481009-A | Methods of producing carboxylic acid ester derivatives and intermediates for use in the methods | FUJIREBIO INC. (JP) | 1996-01-02 | — | — | US | disclosed |
| EP-0643054-A2 | Methods of producing carboxylic acid ester derivatives and intermediates for use in the methods | FUJIREBIO Inc. (JP) | 1995-03-15 | — | — | EP | disclosed |