SCHEMBL8855239

SCHEMBL8855239

COCCOCCOc1c2c(c(C(C)C)c(C=O)c1-c1ccc(F)cc1)CC(C)(C)O2

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 1/20 0.33
MAPK14 Q16539 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8855229 0.97 FFAR4 (0.32) FFAR4
SCHEMBL9085645 0.91 FFAR4 (0.31) FFAR4MAPK14
SCHEMBL9086388 0.87 SQOR (0.30)
SCHEMBL8854976 0.87 SSTR5 (0.33) FFAR4
SCHEMBL8855055 0.86 FFAR4 (0.32) FFAR4MAPK14
SCHEMBL8855047 0.86 PTGS2 (0.33) FFAR4
SCHEMBL8855051 0.85 GCGR (0.37) FFAR4MAPK14
SCHEMBL8854986 0.85 FFAR4 (0.33) FFAR4MAPK14
SCHEMBL8854972 0.83 FFAR4 (0.32) FFAR4
SCHEMBL8855046 0.83 AR (0.36) FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5599952-A A 4-FLUOROBIPHENYL DERIVATIVE FUJIREBIO INC. (JP) 1997-02-04 US disclosed
US-5481009-A Methods of producing carboxylic acid ester derivatives and intermediates for use in the methods FUJIREBIO INC. (JP) 1996-01-02 US disclosed
EP-0643054-A2 Methods of producing carboxylic acid ester derivatives and intermediates for use in the methods FUJIREBIO Inc. (JP) 1995-03-15 EP disclosed