Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | DHFR | P00374 | 3/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7571102 | 0.87 | L3MBTL1 (0.53) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL27660161 | 0.85 | L3MBTL1 (0.47) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8143561 | 0.85 | L3MBTL1 (0.47) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL27660159 | 0.85 | L3MBTL1 (0.47) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8143558 | 0.85 | L3MBTL1 (0.47) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL28757793 | 0.83 | L3MBTL1 (0.51) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL27584197 | 0.83 | L3MBTL1 (0.65) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10758630 | 0.82 | L3MBTL1 (0.55) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10965936 | 0.81 | L3MBTL1 (0.58) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9539332 | 0.80 | L3MBTL1 (0.57) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663339-A | Process for preparing 5-substituted pyrrolo-[2,3-D] pyrimidines | ELI LILLY AND COMPANY (US) | 1997-09-02 | — | — | US | disclosed |
| US-5644058-A | Process for preparing 5-substituted pyrrolo-[2,3-d]pyrimidines | ELI LILLY AND COMPANY (US) | 1997-07-01 | — | — | US | disclosed |
| US-5612482-A | Process for preparing 5-substituted pyrrolo-[2,3-d]pyrimidines | ELI LILLY AND COMPANY (US) | 1997-03-18 | — | — | US | disclosed |
| US-5416211-A | Process for preparing 5-substituted pyrrolo-[2,3-d]pyrimidines | ELI LILLY AND COMPANY (US) | 1995-05-16 | — | — | US | disclosed |
| EP-0589720-A2 | Process for preparing 5-substituted pyrrolo-[2,3-d]pyrimidines | ELI LILLY AND COMPANY (US) | 1994-03-30 | — | — | EP | disclosed |