Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 3/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8143558 | 1.00 | L3MBTL1 (0.47) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8143561 | 1.00 | L3MBTL1 (0.47) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL27660161 | 1.00 | L3MBTL1 (0.47) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7848147 | 0.94 | L3MBTL1 (0.46) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7848146 | 0.94 | L3MBTL1 (0.46) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL27639464 | 0.88 | TAS1R3 (0.46) | L3MBTL1ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL27639462 | 0.88 | TAS1R3 (0.46) | L3MBTL1ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL27639466 | 0.86 | CTSL (0.44) | ALDH1A1HPGDKMT2A | |
| SCHEMBL8855296 | 0.85 | L3MBTL1 (0.49) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7571102 | 0.84 | L3MBTL1 (0.53) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100379729-C | Nitro compounds and their application in preparation of pemetrexed | HAINAN TIANYUAN KANGZE PHARMAC (CN) | 2008-04-09 | — | — | CN | disclosed |
| CN-1827604-A | Nitro compounds and their application in preparation of pemetrexed | HENAN TIANYUAN KANGZE PHARMACE (CN) | 2006-09-06 | — | — | CN | disclosed |