SCHEMBL8855374

SCHEMBL8855374

NC(=C(c1ccccc1)[N+](=O)[O-])c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 1/20 0.44
MAPT P10636 2/20 0.43
TSHR P16473 2/20 0.43
POLB P06746 2/20 0.43
BLM P54132 2/20 0.43
CYP3A4 P08684 1/20 0.43
PARP1 P09874 1/20 0.43
CYP2C19 P33261 1/20 0.43
RECQL P46063 1/20 0.43
PMP22 Q01453 1/20 0.43
HSD17B10 Q99714 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
FBP1 P09467 3/20 0.41
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
MAPK1 P28482 2/20 0.41
ALDH1A1 P00352 2/20 0.41
GAA P10253 1/20 0.39
F2 P00734 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10995027 0.87 PRMT1 (0.54) PRMT1TSHRPOLBTDP1L3MBTL1
SCHEMBL14935500 0.87 PRMT1 (0.54) PRMT1TSHRPOLBTDP1L3MBTL1
SCHEMBL7260785 0.87 PRMT1 (0.54) PRMT1TSHRPOLBTDP1L3MBTL1
SCHEMBL6298584 0.80 ALDH1A1 (0.45) MAPTTSHRHSD17B10CES2CES1
SCHEMBL27711048 0.78 PRMT1 (0.47) PRMT1TSHRPOLBTDP1L3MBTL1
SCHEMBL8413167 0.78 PRMT1 (0.47) PRMT1MAPTTSHRPOLBBLM
SCHEMBL5166975 0.78 PRMT1 (0.47) PRMT1TSHRPOLBTDP1L3MBTL1
SCHEMBL287058 0.77 ALDH1A1 (0.42) PRMT1MAPTTSHRPOLBBLM
SCHEMBL287055 0.77 ALDH1A1 (0.42) PRMT1MAPTTSHRPOLBBLM
SCHEMBL9206410 0.77 FBP1 (0.52) PRMT1MAPTPOLBTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5652327-A Triazine polymers HOECHST AKTIENGESELLSCHAFT (DE) 1997-07-29 US claimed
US-5637370-A CONTAINING ACTIVE POLYMER LAYER POLARIZABLE BY FOCUSSED ELECTRON BEAM BETWEEN AT LEAST ONE ELECTRICALLY-INSULATIVE LAYER AND AT LEAST ONE CONDUCTIVE OR SEMICONDUCTIVE LAYER FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN (DE) 1997-06-10 US claimed
EP-0668529-A2 Triazine polymers HOECHST AKTIENGESELLSCHAFT (DE) 1995-08-23 EP claimed
US-5326661-A Photorefractive polymers containing discrete photoconductive and electrooptical units HOECHST CELANESE CORP. (US) 1994-07-05 US claimed
US-5637370-A CONTAINING ACTIVE POLYMER LAYER POLARIZABLE BY FOCUSSED ELECTRON BEAM BETWEEN AT LEAST ONE ELECTRICALLY-INSULATIVE LAYER AND AT LEAST ONE CONDUCTIVE OR SEMICONDUCTIVE LAYER FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN (DE) 1997-06-10 US disclosed
US-5623475-A Method of inscribing and readout of information in an information storage layer FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 1997-04-22 US disclosed
EP-0668529-A2 Triazine polymers HOECHST AKTIENGESELLSCHAFT (DE) 1995-08-23 EP disclosed
US-5399664-A Electrooptics ARCH DEVELOPMENT CORPORATION (US) 1995-03-21 US disclosed
EP-0326133-B1 Organic nonlinear optical material and nonlinear optical device NIPPON TELEGRAPH & TELEPHONE (JP) 1994-12-07 EP disclosed
US-5326661-A Photorefractive polymers containing discrete photoconductive and electrooptical units HOECHST CELANESE CORP. (US) 1994-07-05 US disclosed
US-5155793-A OPTICAL COMPONENT FOR APPLICATIONS IN INTEGRATED OPTICS THOMSON-CSF (FR) 1992-10-13 US disclosed
EP-0463930-A1 Means for marking objects, method for carrying out and device for reading THOMSON-CSF (FR) 1992-01-02 EP disclosed
EP-0442796-A1 Optical component for applications in integrated optics THOMSON-CSF (FR) 1991-08-21 EP disclosed
US-4999139-A Aminonitrostyrene Compound; Including a Polarizer, an Optical Resonator an a Reflector NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1991-03-12 US disclosed
WO-1991003002-A1 PHOTO-CROSSLINKED POLYMERS FOR NON-LINEAR OPTICS MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1991-03-07 WO disclosed
US-4997595-A Organic nonlinear optical material and nonlinear optical device NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1991-03-05 US disclosed
EP-0326133-A2 Organic nonlinear optical material and nonlinear optical device NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1989-08-02 EP disclosed