SCHEMBL5166975

SCHEMBL5166975

O=[N+]([O-])C(=C([N+](=O)[O-])[N+](=O)[O-])c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 1/20 0.47
ALDH1A1 P00352 3/20 0.44
CES2 O00748 2/20 0.44
CES1 P23141 2/20 0.44
LMNA P02545 1/20 0.41
MAPK1 P28482 2/20 0.40
POLB P06746 2/20 0.40
VCAM1 P19320 1/20 0.40
FBP1 P09467 3/20 0.39
CA2 P00918 1/20 0.39
CA4 P22748 1/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
DAO P14920 1/20 0.39
TSHR P16473 1/20 0.39
NAPRT Q6XQN6 1/20 0.39
TP53 P04637 1/20 0.38
ATM Q13315 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10995027 0.91 PRMT1 (0.54) PRMT1ALDH1A1CES2CES1LMNA
SCHEMBL14935500 0.91 PRMT1 (0.54) PRMT1ALDH1A1CES2CES1LMNA
SCHEMBL7260785 0.91 PRMT1 (0.54) PRMT1ALDH1A1CES2CES1LMNA
SCHEMBL8413167 0.82 PRMT1 (0.47) PRMT1ALDH1A1CES2CES1LMNA
SCHEMBL27711048 0.82 PRMT1 (0.47) PRMT1ALDH1A1CES2CES1LMNA
SCHEMBL9206410 0.80 FBP1 (0.52) PRMT1ALDH1A1CES2CES1LMNA
SCHEMBL10591746 0.79 PRMT1 (0.48) PRMT1ALDH1A1CES2CES1LMNA
SCHEMBL8855374 0.78 PRMT1 (0.44) PRMT1ALDH1A1CES2CES1LMNA
SCHEMBL1174501 0.77 ALDH1A1 (0.44) PRMT1ALDH1A1CES2CES1MAPK1
SCHEMBL28405665 0.77 PRMT1 (0.43) PRMT1ALDH1A1CES2CES1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1733211-A4 PROCESSABLE MOLECULARLY IMPRINTED POLYMERS UNIV JOHNS HOPKINS (US) 2007-05-30 EP claimed
EP-1733211-A1 PROCESSABLE MOLECULARLY IMPRINTED POLYMERS THE JOHNS-HOPKINS UNIVERSITY (US) 2006-12-20 EP claimed
WO-2005103655-A1 PROCESSABLE MOLECULARLY IMPRINTED POLYMERS THE JOHNS HOPKINS UNIVERSITY (US) 2005-11-03 WO claimed
US-12595363-B2 Thermoplastic resin composition and method for producing same KANEKA CORPORATION (JP) 2026-04-07 US disclosed
EP-3597408-B1 BONDED COMPOSITE OF THERMOPLASTIC-RESIN-BASED FIBER-REINFORCED COMPOSITE MATERIAL AND METAL MEMBER, AND METHOD FOR PRODUCING BONDED COMPOSITE KANEKA CORP (JP) 2024-09-18 EP disclosed
EP-3261987-B1 DISPERSING ADDITIVE TECHNISCHE HOCHSCHULE NUERNBERG GEORG SIMON OHM (DE) 2024-08-28 EP disclosed
US-11993740-B2 Low dielectric resin composition, molded article, film, multilayer film and flexible printed wiring board KANEKA CORPORATION (JP) 2024-05-28 US disclosed
US-20220363892-A1 THERMOPLASTIC RESIN COMPOSITION AND METHOD FOR PRODUCING SAME KANEKA CORPORATION (JP) 2022-11-17 US disclosed
CN-115210323-A Thermoplastic resin composition and method for producing same 株式会社钟化 2022-10-18 CN disclosed
WO-2022091960-A1 LAYERED FILM AND COPPER-CLAD LAYERED SHEET 株式会社カネカ 2022-05-05 WO disclosed
CN-114341213-A Polypropylene resin composition, method for producing same, method for producing pre-expanded beads, and method for producing foamed molded article 株式会社钟化 2022-04-12 CN disclosed
US-20220041932-A1 LOW DIELECTRIC RESIN COMPOSITION, MOLDED ARTICLE, FILM, MULTILAYER FILM AND FLEXIBLE PRINTED WIRING BOARD KANEKA CORPORATION (JP) 2022-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12595363-B2 Thermoplastic resin composition and method for producing same RARA, ASIC1, COL2A1 PRMT1 1355/4885ALDH1A1 2101/4885CES2 1519/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.