Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8855455 | 0.94 | MAPT (0.51) | KDM4EMAPTHPGDPOLBCA12 | |
| SCHEMBL4103751 | 0.85 | KDM4E (0.51) | KDM4EMAPTHPGDPOLBGAA | |
| SCHEMBL8855594 | 0.84 | MAPT (0.50) | KDM4EMAPTHPGDPOLBCA12 | |
| SCHEMBL8855590 | 0.81 | MAPT (0.50) | KDM4EMAPTHPGDPOLBGAA | |
| SCHEMBL11875538 | 0.81 | LMNA (0.44) | KDM4EPOLBCA12CA9GAA | |
| SCHEMBL30806283 | 0.77 | ALDH1A1 (0.52) | MAPTHPGDPOLBCA12CA9 | |
| SCHEMBL11875522 | 0.75 | LMNA (0.44) | KDM4EPOLBCA12CA9GAA | |
| SCHEMBL7617288 | 0.75 | SMN1; SMN2 (0.74) | KDM4EMAPTHPGDPOLBSMN1; SMN2 | |
| SCHEMBL5423878 | 0.75 | ALDH1A1 (0.57) | KDM4EMAPTHPGDPOLBSMN1; SMN2 | |
| SCHEMBL29382304 | 0.75 | SMN1; SMN2 (0.74) | KDM4EMAPTHPGDPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670485-A | FEEDS FOR POULTRY WITH O-PHENYLENEDIAMINE OR BENZIMIDAZOLE WITH POLYETHER ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1997-09-23 | — | — | US | disclosed |
| US-3980784-A | Control of animal parasites with benzimidazoles | ELI LILLY AND COMPANY (US) | 1976-09-14 | — | — | US | disclosed |