Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.43 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.43 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8855627 | 0.91 | CYP3A4 (0.43) | CYP3A4TDP1ALDH1A1TSHRHPGD | |
| SCHEMBL8855447 | 0.86 | CYP3A4 (0.39) | CYP3A4TDP1ALDH1A1TSHRHPGD | |
| SCHEMBL8855422 | 0.81 | PLK1 (0.50) | CYP3A4TDP1ALDH1A1TSHRHPGD | |
| SCHEMBL11684355 | 0.79 | TXNRD1 (0.40) | CYP3A4TDP1ALDH1A1TSHRTXNRD1 | |
| SCHEMBL11853403 | 0.79 | CYP3A4 (0.42) | CYP3A4TDP1ALDH1A1TSHRHPGD | |
| SCHEMBL8855511 | 0.78 | MEN1 (0.42) | CYP3A4TDP1ALDH1A1TSHRHPGD | |
| SCHEMBL8855420 | 0.78 | CYP3A4 (0.39) | CYP3A4TDP1ALDH1A1TSHRHPGD | |
| SCHEMBL11854918 | 0.78 | PLK1 (0.41) | CYP3A4TDP1ALDH1A1TSHRHPGD | |
| SCHEMBL8855512 | 0.77 | ALDH1A1 (0.38) | CYP3A4TDP1ALDH1A1TSHRHPGD | |
| SCHEMBL11863501 | 0.76 | CYP3A4 (0.40) | CYP3A4TDP1ALDH1A1TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670485-A | FEEDS FOR POULTRY WITH O-PHENYLENEDIAMINE OR BENZIMIDAZOLE WITH POLYETHER ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1997-09-23 | — | — | US | disclosed |