Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.40 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.40 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TYMS | P04818 | 2/20 | 0.35 |
| ▸ | MPI | P34949 | 1/20 | 0.34 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MITF | O75030 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8855627 | 0.87 | CYP3A4 (0.43) | TXNRD1TXNRD3TXNRD2DCTPP1ALDH1A1 | |
| SCHEMBL11685455 | 0.80 | CREBBP (0.45) | TXNRD1TXNRD3TXNRD2CREBBPDCTPP1 | |
| SCHEMBL8855456 | 0.79 | CYP3A4 (0.43) | TXNRD1TXNRD3TXNRD2DCTPP1ALDH1A1 | |
| SCHEMBL8855447 | 0.77 | CYP3A4 (0.39) | TXNRD1TXNRD3TXNRD2ALDH1A1MAPT | |
| SCHEMBL11584403 | 0.77 | ALDH1A1 (0.42) | ALDH1A1MAPTCYP2C19HTTMEN1 | |
| SCHEMBL11853403 | 0.74 | CYP3A4 (0.42) | TXNRD1TXNRD3TXNRD2DCTPP1ALDH1A1 | |
| SCHEMBL11854918 | 0.73 | PLK1 (0.41) | TXNRD1TXNRD3TXNRD2DCTPP1ALDH1A1 | |
| SCHEMBL8855433 | 0.71 | MAPT (0.40) | TXNRD1TXNRD3TXNRD2DCTPP1ALDH1A1 | |
| SCHEMBL11860077 | 0.70 | LMNA (0.36) | DCTPP1TDP1LMNACYP3A4TSHR | |
| SCHEMBL8855585 | 0.68 | TDP1 (0.44) | TXNRD1TXNRD3TXNRD2DCTPP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4031107-A | Method for introducing amino groups into benzimidazole or imidazopyridine compounds | ELI LILLY AND COMPANY (US) | 1977-06-21 | — | — | US | claimed |
| US-4031107-A | Method for introducing amino groups into benzimidazole or imidazopyridine compounds | ELI LILLY AND COMPANY (US) | 1977-06-21 | — | — | US | disclosed |