Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15262149 | 0.81 | — | — | |
| SCHEMBL3732473 | 0.81 | CRHBP (0.32) | — | |
| SCHEMBL1845751 | 0.81 | — | — | |
| SCHEMBL8855734 | 0.78 | LMNA (0.38) | PARP1 | |
| SCHEMBL8855767 | 0.77 | PARP10 (0.30) | — | |
| SCHEMBL12443797 | 0.76 | CRHBP (0.41) | — | |
| SCHEMBL9442011 | 0.72 | ALDH1A1 (0.43) | — | |
| SCHEMBL5709793 | 0.71 | HTT (0.32) | — | |
| SCHEMBL9942256 | 0.68 | — | — | |
| SCHEMBL19049167 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106211770-B | Chromene and 1,1A, 2,7B tetrahydrochysene cyclopropane as gamma secretase modulators simultaneously [c] chromene pyrido-pyrazine diketone | 辉瑞公司 | 2018-02-06 | — | — | CN | disclosed |
| US-5614510-A | AMMONIUM SALTS | PERSTORP AB (SE) | 1997-03-25 | — | — | US | disclosed |
| WO-1993016705-A1 | A PHARMACEUTICAL COMPOSITION WITH IMPROVED BIOAVAILABILITY OF INOSITOL PHOSPHATE | PERSTORP AB (SE) | 1993-09-02 | — | — | WO | disclosed |