Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.47 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | MEN1 | O00255 | 7/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7175332 | 1.00 | THRB (0.48) | THRBKMT2AMAPTMEN1MAPK1 | |
| SCHEMBL7175326 | 1.00 | THRB (0.48) | THRBKMT2AMAPTMEN1MAPK1 | |
| SCHEMBL626265 | 0.86 | KMT2A (0.52) | THRBKMT2AMAPTMEN1MAPK1 | |
| SCHEMBL7179907 | 0.86 | CYP1A2 (0.48) | THRBKMT2AMAPTMEN1MAPK1 | |
| SCHEMBL7179903 | 0.86 | CYP1A2 (0.48) | THRBKMT2AMAPTMEN1MAPK1 | |
| SCHEMBL7178612 | 0.84 | CYP1A2 (0.42) | THRBKMT2AMAPTMEN1MAPK1 | |
| SCHEMBL718829 | 0.83 | MAPT (0.47) | THRBKMT2AMAPTMEN1MAPK1 | |
| SCHEMBL373328 | 0.83 | MAPT (0.47) | THRBKMT2AMAPTMEN1MAPK1 | |
| SCHEMBL373229 | 0.83 | MAPT (0.47) | THRBKMT2AMAPTMEN1MAPK1 | |
| SCHEMBL1802886 | 0.83 | MAPT (0.47) | THRBKMT2AMAPTMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5661194-A | POLYMER FROM MONOMERS OF (METH)ACRYLAMIDE TYPE MONOMER, FLUOROALKYL (SILICON-CONTAINING ALKYL) FUMARATE MONOMER, AND CROSSLINKING MONOMER | MENICON CO., LTD. (JP) | 1997-08-26 | — | — | US | disclosed |
| EP-0722110-A2 | Water absorptive soft contact lens | Menicon Co., Ltd. (JP) | 1996-07-17 | — | — | EP | disclosed |