Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 13/20 | 0.61 |
| ▸ | EDNRB | P24530 | 12/20 | 0.61 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8543285 | 0.87 | EDNRB (0.69) | EDNRAEDNRB | |
| SCHEMBL8540948 | 0.85 | EDNRA (0.72) | EDNRAEDNRB | |
| SCHEMBL8590639 | 0.83 | EDNRA (0.64) | EDNRAEDNRB | |
| SCHEMBL8856815 | 0.83 | EDNRB (0.74) | EDNRAEDNRB | |
| SCHEMBL8857065 | 0.83 | EDNRA (0.55) | EDNRAEDNRB | |
| SCHEMBL8856638 | 0.82 | EDNRA (0.78) | EDNRAEDNRB | |
| SCHEMBL8540470 | 0.81 | EDNRB (0.66) | EDNRAEDNRB | |
| SCHEMBL8543571 | 0.81 | EDNRB (0.69) | EDNRAEDNRB | |
| SCHEMBL8545866 | 0.81 | EDNRA (0.66) | EDNRAEDNRB | |
| SCHEMBL8856895 | 0.81 | EDNRB (0.71) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684032-A | ANTIINFLAMMATORY AGENTS, ANTIARTHRITIC, ANTIASTHMATIC AGENTS AND RESPIRATORY DISORDERS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-11-04 | — | — | US | claimed |
| US-5684032-A | ANTIINFLAMMATORY AGENTS, ANTIARTHRITIC, ANTIASTHMATIC AGENTS AND RESPIRATORY DISORDERS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-11-04 | — | — | US | disclosed |