Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.42 |
| ▸ | AHR | P35869 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CDC14B | O60729 | 1/20 | 0.39 |
| ▸ | CDC14A | Q9UNH5 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12411501 | 0.89 | MEN1 (0.55) | MEN1KMT2ACYP2C19ALOX5AHR | |
| SCHEMBL25049910 | 0.82 | MEN1 (0.50) | MEN1KMT2ACYP2C19ALOX5AHR | |
| SCHEMBL28264661 | 0.81 | CYP2C19 (0.51) | MEN1KMT2ACYP2C19ALOX5AHR | |
| SCHEMBL18022257 | 0.79 | ALOX5 (0.53) | MEN1KMT2ACYP2C19ALOX5AHR | |
| SCHEMBL17299529 | 0.77 | MEN1 (0.46) | MEN1KMT2ACYP2C19ALOX5AHR | |
| SCHEMBL4554342 | 0.76 | ALOX5 (0.54) | MEN1KMT2ACYP2C19ALOX5AHR | |
| SCHEMBL22171903 | 0.75 | MAOA (0.58) | MEN1KMT2ACYP2C19KDM4EALDH1A1 | |
| SCHEMBL17814813 | 0.75 | CYP2C19 (0.54) | MEN1KMT2ACYP2C19ALOX5AHR | |
| SCHEMBL22740859 | 0.75 | LMNA (0.44) | MEN1KMT2ACYP2C19ALOX5AHR | |
| SCHEMBL21971529 | 0.75 | ALOX5 (0.49) | MEN1KMT2ACYP2C19ALOX5AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0642510-A4 | BISMALEIMIDE COMPOUNDS. | COMMW SCIENT IND RES ORG (AU) | 1997-04-02 | — | — | EP | claimed |
| US-5616666-A | CURABLE COMPOSITION FREE OF OLIGOMERIC, AMIDIC AND UNCYCLIZED IMPURITIES; USEFUL IN IMPREGNATED FIBER REINFORCED MATERIALS AND ADVANCED COMPOSITES | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1997-04-01 | — | — | US | claimed |
| EP-0642510-A1 | BISMALEIMIDE COMPOUNDS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1995-03-15 | — | — | EP | claimed |
| WO-1993024488-A1 | BISMALEIMIDE COMPOUNDS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1993-12-09 | — | — | WO | claimed |
| EP-0642510-A4 | BISMALEIMIDE COMPOUNDS. | COMMW SCIENT IND RES ORG (AU) | 1997-04-02 | — | — | EP | disclosed |
| US-5616666-A | CURABLE COMPOSITION FREE OF OLIGOMERIC, AMIDIC AND UNCYCLIZED IMPURITIES; USEFUL IN IMPREGNATED FIBER REINFORCED MATERIALS AND ADVANCED COMPOSITES | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1997-04-01 | — | — | US | disclosed |
| EP-0642510-A1 | BISMALEIMIDE COMPOUNDS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1995-03-15 | — | — | EP | disclosed |
| WO-1993024488-A1 | BISMALEIMIDE COMPOUNDS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1993-12-09 | — | — | WO | disclosed |