Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | EDNRB | P24530 | 5/20 | 0.45 |
| ▸ | EDNRA | P25101 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6308654 | 0.86 | EDNRB (0.55) | MEN1KMT2AEDNRBEDNRAALDH1A1 | |
| SCHEMBL8543832 | 0.83 | ELANE (0.44) | ELANEMEN1KMT2AEDNRBEDNRA | |
| SCHEMBL8539775 | 0.80 | LMNA (0.51) | MEN1KMT2AEDNRBEDNRAALDH1A1 | |
| SCHEMBL5216535 | 0.79 | CCR2 (0.59) | ALDH1A1MAPTGAAHPGDLMNA | |
| SCHEMBL14584200 | 0.77 | ELANE (0.61) | ELANEALDH1A1KDM4ENPSR1HPGD | |
| SCHEMBL8546889 | 0.77 | LMNA (0.51) | MEN1KMT2AEDNRBEDNRAALDH1A1 | |
| SCHEMBL8546146 | 0.77 | EDNRB (0.58) | KMT2AEDNRBEDNRA | |
| SCHEMBL8616220 | 0.76 | MAPT (0.51) | MEN1KMT2AEDNRBEDNRAALDH1A1 | |
| SCHEMBL8543272 | 0.76 | EDNRB (0.60) | KMT2AEDNRBEDNRA | |
| SCHEMBL8545376 | 0.75 | EDNRB (0.59) | EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684032-A | ANTIINFLAMMATORY AGENTS, ANTIARTHRITIC, ANTIASTHMATIC AGENTS AND RESPIRATORY DISORDERS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-11-04 | — | — | US | disclosed |