Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | THRB | P10828 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8857440 | 0.89 | HPGD (0.43) | POLBMAPTTHRBGAATP53 | |
| SCHEMBL8857706 | 0.89 | KMT2A (0.52) | POLBMAPTTHRBGAAALDH1A1 | |
| SCHEMBL8857395 | 0.88 | POLB (0.38) | POLBMAPTTHRBGAATP53 | |
| SCHEMBL8679131 | 0.76 | MAPT (0.41) | POLBMAPTTHRBGAATP53 | |
| SCHEMBL6032173 | 0.73 | MAPT (0.54) | POLBMAPTTHRBGAATP53 | |
| SCHEMBL8857258 | 0.73 | KDM4E (0.40) | MAPTALDH1A1MEN1KMT2AADRB2 | |
| SCHEMBL8657475 | 0.71 | POLB (0.41) | POLBMAPTTHRBGAATP53 | |
| SCHEMBL7469304 | 0.71 | POLB (0.55) | POLBMAPTTHRBGAATP53 | |
| SCHEMBL3774750 | 0.68 | POLB (0.46) | POLBMAPTTHRBGAATP53 | |
| SCHEMBL8577730 | 0.67 | POLB (0.37) | POLBMAPTTHRBGAATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688823-A | ANTILIPEMIC AGENTS, ANTIGLYCEMIC AGENTS, OBESITY, GLUCOSE TOLERANCE INSUFFICIENCY, INSULIN RESISTANCE AND DIABETIC COMPLICATIONS | SANKYO COMPANY, LIMITED (JP) | 1997-11-18 | — | — | US | disclosed |