Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 4/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 8/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8857701 | 0.89 | KMT2A (0.52) | MEN1ALDH1A1KMT2AADRB2ADRB1 | |
| SCHEMBL8857435 | 0.89 | HPGD (0.41) | KDM4EMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL8484201 | 0.81 | SIGMAR1 (0.45) | KDM4EMAPT | |
| SCHEMBL8485569 | 0.79 | MAPT (0.39) | KDM4EMAPTALDH1A1PPARGCYP1A2 | |
| SCHEMBL6032172 | 0.73 | MAPT (0.53) | KDM4EMAPTALDH1A1KMT2APPARG | |
| SCHEMBL8857264 | 0.73 | POLB (0.41) | MAPTMEN1ALDH1A1KMT2AADRB2 | |
| SCHEMBL8974649 | 0.73 | FFAR1 (0.53) | MAPTMEN1ALDH1A1KMT2APPARG | |
| SCHEMBL8486705 | 0.73 | PPARG (0.39) | KDM4EMAPTPPARGCYP3A4CYP2C9 | |
| SCHEMBL7469293 | 0.71 | MAPT (0.56) | KDM4EMAPTMEN1KMT2APPARG | |
| SCHEMBL8664520 | 0.71 | PPARG (0.56) | KDM4EMAPTPPARGCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688823-A | ANTILIPEMIC AGENTS, ANTIGLYCEMIC AGENTS, OBESITY, GLUCOSE TOLERANCE INSUFFICIENCY, INSULIN RESISTANCE AND DIABETIC COMPLICATIONS | SANKYO COMPANY, LIMITED (JP) | 1997-11-18 | — | — | US | disclosed |