Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.67 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.64 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.64 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.64 |
| ▸ | FAAH | O00519 | 3/20 | 0.57 |
| ▸ | CES1 | P23141 | 3/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28721538 | 0.98 | MAPT (0.63) | MAPTRXFP1HDAC1HDAC2ALOX5 | |
| SCHEMBL15941625 | 0.86 | MAPT (0.50) | MAPTRXFP1HDAC1HDAC2ALOX5 | |
| SCHEMBL2322246 | 0.84 | KEAP1 (0.61) | MAPTRXFP1HDAC1HDAC2ALOX5 | |
| SCHEMBL13892460 | 0.84 | MAPT (0.65) | MAPTRXFP1HDAC1HDAC2ALOX5 | |
| SCHEMBL24504176 | 0.81 | MAPT (0.61) | MAPTRXFP1HDAC1HDAC2ALOX5 | |
| Formic Acid SCHEMBL6511593 | 0.81 | MAPT (0.85) | MAPTRXFP1HDAC1HDAC2ALOX5 | |
| SCHEMBL1008045 | 0.80 | MAPT (1.00) | MAPTRXFP1HDAC1HDAC2ALOX5 | |
| SCHEMBL770290 | 0.80 | MAPT (1.00) | MAPTRXFP1HDAC1HDAC2ALOX5 | |
| SCHEMBL2553009 | 0.80 | MAPT (1.00) | MAPTRXFP1HDAC1HDAC2ALOX5 | |
| SCHEMBL2555645 | 0.80 | MAPT (1.00) | MAPTRXFP1HDAC1HDAC2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663318-A | WHEREIN POLYNUCLEOTIDE MEMBERS BOUND TO SUBSTRATE ARE HYBRIDIZABLE WITH TARGET POLYNUCLEOTIDE TO IMMOBILIZE AND DETECT IT | PEGG RANDALL KEVIN (US) | 1997-09-02 | — | — | US | disclosed |
| US-5436147-A | Hydrophobic group on molecule for bonding to substrate | NUCLEIC ASSAYS CORPORATION (US) | 1995-07-25 | — | — | US | disclosed |