Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8858178 | 0.99 | MEN1 (0.41) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL8858111 | 0.96 | LMNA (0.41) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL7316074 | 0.93 | ALDH1A1 (0.47) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL8858206 | 0.92 | MEN1 (0.42) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL8858136 | 0.91 | MEN1 (0.41) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL7307187 | 0.91 | LMNA (0.46) | MEN1KMT2AALDH1A1GAAL3MBTL1 | |
| SCHEMBL8858157 | 0.91 | MEN1 (0.42) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL8858164 | 0.90 | MEN1 (0.44) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL8858181 | 0.89 | L3MBTL1 (0.34) | MEN1KMT2AKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL8858177 | 0.89 | ALDH1A1 (0.43) | MEN1KMT2AKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5627197-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-05-06 | — | — | US | disclosed |