SCHEMBL8858232

SCHEMBL8858232

CCCC=C(CCC)C(=O)OCCCCCC

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
NAAA Q02083 1/20 0.46
HCAR2 Q8TDS4 2/20 0.44
RAD52 P43351 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
EPHX1 P07099 1/20 0.43
DGKA P23743 1/20 0.42
HTR2C P28335 1/20 0.41
FAAH O00519 4/20 0.41
EPHX2 P34913 2/20 0.40
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8858229 1.00 TSHR (0.50) TSHRNAAAHCAR2RAD52NPSR1
SCHEMBL22440066 0.88 NAAA (0.52) TSHRNAAAHCAR2RAD52NPSR1
SCHEMBL17728023 0.88 DGKA (0.52) TSHRNPSR1DGKAFAAHLMNA
SCHEMBL4990203 0.88 NAAA (0.52) TSHRNAAAHCAR2RAD52NPSR1
SCHEMBL6114366 0.87 TSHR (0.50) TSHRNAAAHCAR2RAD52NPSR1
SCHEMBL8468015 0.87 TSHR (0.50) TSHRNAAAHCAR2RAD52NPSR1
SCHEMBL10578070 0.86 HCAR2 (0.37) TSHRHCAR2DGKAFAAHALDH1A1
SCHEMBL22070461 0.85 TSHR (0.47) TSHRNAAAHCAR2RAD52NPSR1
SCHEMBL1700779 0.84 MGLL (0.46) TSHRNPSR1DGKAFAAHEPHX2
SCHEMBL27884984 0.83 TSHR (0.46) TSHRNAAAHCAR2RAD52NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5614480-A OVERBASED COMPOUNDS THE LUBRIZOL CORPORATION (US) 1997-03-25 US disclosed
US-5562864-A OIL WITH ONE CARBOXY DERIVATIVE FORMED BY ACYLATION OF SUCCINIC ACID AND A MIXTURE OF OVERBASED SALT OF CARBOXYLIC ACID, OR ACID WITH SULFONIC ACID WITH MAGNESIUM OR CALCIUM COMPOUNDS THE LUBRIZOL CORPORATION (US) 1996-10-08 US disclosed
US-5490945-A OIL CONTAINING CARBOXYLIC MODIFIED POLYOLEFIN THE LUBRIZOL CORPORATION (US) 1996-02-13 US disclosed
EP-0596047-A1 LUBRICATING COMPOSITIONS AND CONCENTRATES THE LUBRIZOL CORPORATION (US) 1994-05-11 EP disclosed
EP-0596048-A1 LUBRICATING COMPOSITIONS AND CONCENTRATES THE LUBRIZOL CORPORATION (US) 1994-05-11 EP disclosed
WO-1993023504-A1 LUBRICATING COMPOSITIONS AND CONCENTRATES THE LUBRIZOL CORPORATION (US) 1993-11-25 WO disclosed
WO-1993023505-A1 LUBRICATING COMPOSITIONS AND CONCENTRATES THE LUBRIZOL CORPORATION (US) 1993-11-25 WO disclosed