Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 12/20 | 0.61 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8858542 | 0.92 | PTGIR (0.58) | PTGIRPTGDRTSHRUSP2LMNA | |
| SCHEMBL8858416 | 0.90 | PTGIR (0.57) | PTGIRPTGDRLMNAMAPTSIGMAR1 | |
| SCHEMBL8858459 | 0.87 | PTGIR (0.50) | PTGIRPTGDRUSP2LMNAMAPT | |
| SCHEMBL9049403 | 0.86 | PTGIR (0.45) | PTGIRPTGDRTSHRSLC6A9SLC6A5 | |
| SCHEMBL9049399 | 0.81 | KMT2A (0.41) | PTGIRPTGDRTSHRMAPTSLC6A9 | |
| SCHEMBL9014489 | 0.79 | PTGIR (0.58) | PTGIRPTGDRSIGMAR1 | |
| SCHEMBL9568093 | 0.78 | ALDH1A1 (0.45) | TSHRSLC6A9SLC6A5SIGMAR1KMT2A | |
| SCHEMBL9014581 | 0.77 | PTGIR (0.58) | PTGIRPTGDRMAPTMAPK1HTT | |
| SCHEMBL9049336 | 0.74 | PTGIR (0.39) | PTGIRPTGDRTSHRMAPTSLC6A9 | |
| SCHEMBL8414122 | 0.74 | PTGIR (0.63) | PTGIRPTGDRSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | claimed |
| US-5596009-A | TREATMENT OF THROMBOSIS, ATHERIOSCLEROSIS, ANTIISCHEMIC AGENTS, ANTIULCER AGENTS OR HYPOTENSIVE AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-01-21 | — | — | US | disclosed |
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | disclosed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | disclosed |