Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9049399 | 0.92 | KMT2A (0.41) | PTGIRKMT2AL3MBTL1MEN1SLC6A9 | |
| SCHEMBL9568057 | 0.85 | ALDH1A1 (0.39) | PTGIRKMT2AL3MBTL1MEN1SLC6A9 | |
| SCHEMBL8858542 | 0.84 | PTGIR (0.58) | PTGIRMAPTPTGDRTSHRTDP1 | |
| SCHEMBL9050019 | 0.81 | PTGIR (0.38) | PTGIRKMT2AL3MBTL1MEN1 | |
| SCHEMBL9051425 | 0.80 | PTGIR (0.33) | PTGIRKMT2AL3MBTL1MEN1SLC6A9 | |
| SCHEMBL9568093 | 0.75 | ALDH1A1 (0.45) | KMT2AL3MBTL1MEN1SLC6A9SLC6A5 | |
| SCHEMBL9049403 | 0.74 | PTGIR (0.45) | PTGIRKMT2AL3MBTL1MEN1SLC6A9 | |
| SCHEMBL8858403 | 0.74 | PTGIR (0.61) | PTGIRKMT2AL3MBTL1SLC6A9SLC6A5 | |
| SCHEMBL8858416 | 0.66 | PTGIR (0.57) | PTGIRKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL8858459 | 0.66 | PTGIR (0.50) | PTGIRMAPTPTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | claimed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | claimed |
| EP-0542203-B1 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO (JP) | 1996-07-03 | — | — | EP | disclosed |
| US-5344836-A | Fused benzeneoxyacetic acid derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-09-06 | — | — | US | disclosed |