Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 8/20 | 0.42 |
| ▸ | DRD3 | P35462 | 7/20 | 0.42 |
| ▸ | DRD4 | P21917 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | PTGIR | P43119 | 6/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8858434 | 0.85 | KMT2A (0.43) | MTNR1AMTNR1BCHRM2CHRM1CHRM3 | |
| SCHEMBL8858426 | 0.81 | PTGIR (0.48) | MTNR1AMTNR1BCHRM2CHRM1CHRM3 | |
| SCHEMBL8858413 | 0.79 | PTGIR (0.46) | MTNR1AMTNR1BCHRM2CHRM1CHRM3 | |
| SCHEMBL8858429 | 0.75 | PTGIR (0.59) | PTGIR | |
| SCHEMBL8858427 | 0.75 | MTNR1A (0.41) | MTNR1AMTNR1BCHRM2CHRM1CHRM3 | |
| SCHEMBL8858425 | 0.75 | MTNR1A (0.43) | MTNR1AMTNR1BCHRM2CHRM1CHRM3 | |
| SCHEMBL9005706 | 0.71 | PTGIR (0.47) | DRD2DRD3DRD4PTGIR | |
| SCHEMBL8858475 | 0.68 | KDM4C (0.44) | PTGIR | |
| SCHEMBL9037155 | 0.68 | CHRM2 (0.53) | MTNR1AMTNR1BCHRM2CHRM1CHRM3 | |
| SCHEMBL8858435 | 0.68 | HTR1A (0.36) | MTNR1AMTNR1BCHRM3DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5596009-A | TREATMENT OF THROMBOSIS, ATHERIOSCLEROSIS, ANTIISCHEMIC AGENTS, ANTIULCER AGENTS OR HYPOTENSIVE AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-01-21 | — | — | US | disclosed |