Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 9/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
| ▸ | CCR3 | P51677 | 1/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.45 |
| ▸ | F11 | P03951 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568009 | 0.82 | LMNA (0.56) | PSMB5ALDH1A1HTTSMN1; SMN2PRMT5 | |
| SCHEMBL9049799 | 0.82 | F11 (0.42) | PSMB5ALDH1A1HTTNCOA1SMN1; SMN2 | |
| SCHEMBL9568008 | 0.81 | ALDH1A1 (0.51) | PSMB5ALDH1A1HTTNCOA1SMN1; SMN2 | |
| SCHEMBL9567979 | 0.80 | ALDH1A1 (0.49) | PSMB5ALDH1A1HTTNCOA1SMN1; SMN2 | |
| SCHEMBL8858477 | 0.79 | PTGIR (0.52) | F11 | |
| SCHEMBL9567989 | 0.79 | PRMT5 (0.60) | PSMB5ALDH1A1HTTPRMT5WDR77 | |
| SCHEMBL7398455 | 0.77 | ALDH1A1 (0.57) | PSMB5ALDH1A1HTTPRMT5WDR77 | |
| SCHEMBL9568169 | 0.76 | PRMT5 (0.52) | PSMB5ALDH1A1HTTPRMT5WDR77 | |
| SCHEMBL9568003 | 0.74 | PRMT5 (0.47) | PSMB5ALDH1A1HTTPRMT5WDR77 | |
| SCHEMBL9269083 | 0.72 | KMT2A (0.62) | HTTPRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |