Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.41 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 2/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8858581 | 1.00 | NPC1 (0.42) | NPC1ALDH1A1MAPK1TDP1MAPT | |
| SCHEMBL27543593 | 0.72 | NPC1 (0.49) | NPC1LMNAACHERAB9AL3MBTL1 | |
| SCHEMBL6835126 | 0.71 | L3MBTL1 (0.41) | NPC1ALDH1A1MAPK1RECQLLMNA | |
| SCHEMBL29006674 | 0.70 | MAPT (0.68) | NPC1ALDH1A1MAPTRECQLLMNA | |
| SCHEMBL29006676 | 0.70 | MAPT (0.68) | NPC1ALDH1A1MAPTRECQLLMNA | |
| SCHEMBL576636 | 0.69 | NPC1 (0.69) | NPC1ALDH1A1MAPK1TDP1RECQL | |
| SCHEMBL2680021 | 0.68 | ALDH1A1 (0.56) | NPC1ALDH1A1MAPK1TDP1MAPT | |
| SCHEMBL1370683 | 0.68 | ALDH1A1 (0.56) | NPC1ALDH1A1MAPK1TDP1MAPT | |
| Benzene SCHEMBL27436197 | 0.68 | ALDH1A1 (0.56) | NPC1ALDH1A1MAPK1TDP1MAPT | |
| SCHEMBL105986 | 0.68 | ALDH1A1 (0.56) | NPC1ALDH1A1MAPK1TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5608109-A | AGRICULTURAL AND HORTICULTURAL INSECTICIDE | NIHON NOHYAKU CO., LTD. (JP) | 1997-03-04 | — | — | US | disclosed |
| EP-0657421-A1 | Hydrazine derivatives and their use as insecticides | NIHON NOHYAKU CO., LTD. (JP) | 1995-06-14 | — | — | EP | disclosed |