Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 9/20 | 0.49 |
| ▸ | RET | P07949 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 8/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ACP3 | P15309 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7167654 | 0.82 | HTR2A (0.59) | HTR2ARETHRH1HTR2CCHRM1 | |
| SCHEMBL8201075 | 0.79 | HTR2A (0.55) | HTR2ARETHRH1HTR2CCHRM1 | |
| SCHEMBL11229592 | 0.75 | ALDH1A1 (0.39) | HTR2ADRD2ADRA2BADRA2CADRA1A | |
| SCHEMBL9875531 | 0.74 | HTR2A (0.63) | HTR2ARETHRH1HTR2CCHRM1 | |
| SCHEMBL8712643 | 0.74 | RET (0.44) | HTR2ARETACP3IDO1 | |
| Di(Hydroxyethyl)Ether SCHEMBL6251141 | 0.72 | TSHR (0.50) | HTR2CMEN1KMT2AIDO1 | |
| SCHEMBL11837153 | 0.71 | HTR2A (0.46) | HTR2ARETHRH1HTR2CCHRM1 | |
| SCHEMBL24631299 | 0.71 | HTR2A (0.66) | HTR2ARETHRH1HTR2C | |
| SCHEMBL8255138 | 0.71 | HTR2A (0.78) | HTR2ARETHRH1HTR2CCHRM1 | |
| SCHEMBL11220205 | 0.70 | ALDH1A1 (0.45) | HTR2ADRD2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997022342-A1 | NOVEL METHOD | NOVO NORDISK A/S (DK) | 1997-06-26 | — | — | WO | disclosed |
| EP-0585314-B1 | NOVEL HETEROCYCLIC CARBOXYLIC ACIDS | NOVO NORDISK AS (DK) | 1996-09-18 | — | — | EP | disclosed |
| US-5348965-A | N-substituted azaheterocyclic carboxylic acids | NOVO NORDISK A/S (DK) | 1994-09-20 | — | — | US | disclosed |
| EP-0585314-A1 | NOVEL HETEROCYCLIC CARBOXYLIC ACIDS. | NOVO NORDISK AS (DK) | 1994-03-09 | — | — | EP | disclosed |
| WO-1992020658-A1 | NOVEL HETEROCYCLIC CARBOXYLIC ACIDS | NOVO NORDISK A/S (DK) | 1992-11-26 | — | — | WO | disclosed |