SCHEMBL8859481

SCHEMBL8859481

c1ccc(-c2ccc(Nc3ccc(Nc4ccc(-c5ccccc5)cc4)cc3)cc2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.71
HSD17B10 Q99714 6/20 0.71
TDP1 Q9NUW8 4/20 0.71
ALOX12 P18054 3/20 0.71
L3MBTL1 Q9Y468 3/20 0.71
TSHR P16473 3/20 0.71
ALOX15 P16050 2/20 0.71
MAPK1 P28482 2/20 0.71
PTGS1 P23219 1/20 0.71
SLC6A2 P23975 1/20 0.71
PTGS2 P35354 1/20 0.71
HTR2B P41595 1/20 0.71
CYP3A4 P08684 5/20 0.55
HTT P42858 3/20 0.55
MAPT P10636 2/20 0.55
HPGD P15428 2/20 0.55
CYP1A2 P05177 2/20 0.55
CYP2C9 P11712 1/20 0.55
CYP2C19 P33261 1/20 0.55
MEN1 O00255 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL428698 1.00 ALDH1A1 (0.71) ALDH1A1HSD17B10TDP1ALOX12L3MBTL1
SCHEMBL21514977 1.00 ALDH1A1 (0.71) ALDH1A1HSD17B10TDP1ALOX12L3MBTL1
SCHEMBL68489 1.00 ALDH1A1 (0.71) ALDH1A1HSD17B10TDP1ALOX12L3MBTL1
SCHEMBL4554396 1.00 ALDH1A1 (0.71) ALDH1A1HSD17B10TDP1ALOX12L3MBTL1
SCHEMBL5370467 1.00 ALDH1A1 (0.71) ALDH1A1HSD17B10TDP1ALOX12L3MBTL1
SCHEMBL10034432 1.00 ALDH1A1 (0.71) ALDH1A1HSD17B10TDP1ALOX12L3MBTL1
SCHEMBL431535 0.97 ALDH1A1 (0.77) ALDH1A1HSD17B10TDP1ALOX12L3MBTL1
SCHEMBL14160282 0.97 ALDH1A1 (0.77) ALDH1A1HSD17B10TDP1ALOX12L3MBTL1
SCHEMBL10079561 0.97 ALDH1A1 (0.77) ALDH1A1HSD17B10TDP1ALOX12L3MBTL1
SCHEMBL12367618 0.97 ALDH1A1 (0.77) ALDH1A1HSD17B10TDP1ALOX12L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2796448-B1 Material for organic electronic device and organic electronic device using the same LG CHEMICAL LTD (KR) 2018-04-25 EP disclosed
US-9722188-B2 Material for organic electronic device, and organic electronic device using the same LG CHEM, LTD. (KR) 2017-08-01 US disclosed
EP-1775335-B9 Organic electroluminescent element IDEMITSU KOSAN CO (JP) 2013-06-26 EP disclosed
US-20120153815-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2012-06-21 US disclosed
US-20120153815-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2012-06-21 US disclosed
EP-1775335-B1 Organic electroluminescent element IDEMITSU KOSAN CO (JP) 2012-05-23 EP disclosed
US-20110175521-A1 ORGANIC ELECTROLUMESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2011-07-21 US disclosed
US-20110175521-A1 ORGANIC ELECTROLUMESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2011-07-21 US disclosed
US-20100160687-A1 ORGANIC ELECTROLUMESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-06-24 US disclosed
US-20100160687-A1 ORGANIC ELECTROLUMESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-06-24 US disclosed
US-20070142671-A1 ORGANIC ELECTROLUMESCENCE DEVICE IDEMITSU KOSAN CO., LTD (JP) 2007-06-21 US disclosed
US-20070142671-A1 ORGANIC ELECTROLUMESCENCE DEVICE IDEMITSU KOSAN CO., LTD (JP) 2007-06-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110175521-A1 ORGANIC ELECTROLUMESCENCE DEVICE SCO2, CHRM1, CHRM4 ALDH1A1 2388/4885HSD17B10 2146/4885TDP1 2598/4885
US-20100160687-A1 ORGANIC ELECTROLUMESCENCE DEVICE SCO2, CHRM1, CHRM4 ALDH1A1 2388/4885HSD17B10 2146/4885TDP1 2598/4885
US-20120153815-A1 ORGANIC ELECTROLUMINESCENCE DEVICE ARL1, RIF1, EML4 ALDH1A1 699/4885HSD17B10 3421/4885TDP1 2733/4885
US-20070142671-A1 ORGANIC ELECTROLUMESCENCE DEVICE SCO2, CHRM1, CHRM4 ALDH1A1 2388/4885HSD17B10 2146/4885TDP1 2598/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.