Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CES2 | O00748 | 4/20 | 0.41 |
| ▸ | CES1 | P23141 | 4/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 5/20 | 0.38 |
| ▸ | PPARD | Q03181 | 5/20 | 0.38 |
| ▸ | PPARA | Q07869 | 5/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.38 |
| ▸ | TLR2 | O60603 | 2/20 | 0.38 |
| ▸ | FABP4 | P15090 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3717342 | 0.94 | LMNA (0.45) | LMNACA2FFAR4FFAR1ALDH1A1 | |
| SCHEMBL7754824 | 0.94 | LMNA (0.50) | LMNACA2FFAR4FFAR1ALDH1A1 | |
| SCHEMBL8859475 | 0.92 | LMNA (0.43) | LMNACA2FFAR4FFAR1ALDH1A1 | |
| SCHEMBL8756867 | 0.91 | LMNA (0.44) | LMNACA2FFAR4FFAR1ALDH1A1 | |
| SCHEMBL8859572 | 0.88 | CA2 (0.53) | LMNACA2FFAR4FFAR1ALDH1A1 | |
| SCHEMBL15135076 | 0.87 | CA2 (0.42) | LMNACA2ALDH1A1CES2CES1 | |
| SCHEMBL8756838 | 0.87 | LMNA (0.44) | LMNACA2FFAR4FFAR1ALDH1A1 | |
| SCHEMBL8758073 | 0.85 | LMNA (0.47) | LMNACA2FFAR4FFAR1ALDH1A1 | |
| SCHEMBL8757657 | 0.84 | LMNA (0.41) | LMNACA2FFAR4FFAR1ALDH1A1 | |
| SCHEMBL713127 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5672730-A | OXIDATION RESIST STABILIZER FOR POLYMERIC BLENDS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-09-30 | — | — | US | disclosed |