Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.39 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8859573 | 0.94 | LMNA (0.46) | LMNACA2FFAR1FFAR4GPR84 | |
| SCHEMBL8758073 | 0.91 | LMNA (0.47) | LMNACA2FFAR1FFAR4GPR84 | |
| SCHEMBL7756664 | 0.90 | CA2 (0.48) | LMNACA2FFAR1FFAR4GPR84 | |
| SCHEMBL8859475 | 0.90 | LMNA (0.43) | LMNACA2FFAR1FFAR4GPR84 | |
| SCHEMBL15135076 | 0.89 | CA2 (0.42) | LMNACA2ALDH1A1NFKB1HDAC3 | |
| SCHEMBL3717342 | 0.88 | LMNA (0.45) | LMNACA2FFAR1FFAR4GPR84 | |
| SCHEMBL8859572 | 0.86 | CA2 (0.53) | LMNACA2FFAR1FFAR4ALDH1A1 | |
| SCHEMBL8756838 | 0.85 | LMNA (0.44) | LMNACA2FFAR1FFAR4GPR84 | |
| SCHEMBL8756867 | 0.85 | LMNA (0.44) | LMNACA2FFAR1FFAR4GPR84 | |
| SCHEMBL15135067 | 0.85 | CA2 (0.36) | LMNACA2ALDH1A1NFKB1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0764636-B1 | Thiopropionate synergists | GOODYEAR TIRE & RUBBER (US) | 2001-03-07 | — | — | EP | disclosed |
| US-5672730-A | OXIDATION RESIST STABILIZER FOR POLYMERIC BLENDS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-09-30 | — | — | US | disclosed |